Durability of antiviral therapy for chronic hepatitis C after achieving sustained virological response

Efficacy of regimens containing pegylated interferon and ribavirin in the treatment of chronic hepatitis C: A retrospective overview

“…These inconsistencies result from PCR methods used in varying sensitivity and patient populations. As a result, continuity of the sustained viral response and optimal follow-up time are not known (28). With regards to the response status of PEG-IFN α-2A + RIB and PEG-IFN α-2B + RIB treatment in genotype sub-groups in our study, among 284 patients with genotype 1b; sustained viral response, unresponsiveness to treatment and recurrence were seen in 129 (45.4%), 86 (30.3%), and 35 (12.3%) patients.…”