2021
DOI: 10.1101/2021.05.04.442699
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Durable antibody responses in staff at two long-term care facilities, during and post SARS-CoV-2 outbreaks

Abstract: SARS-CoV-2 has had a disproportionate impact on non-hospital healthcare settings such as long-term care facilities (LTCFs). The communal nature of these facilities, paired with the high-risk profile of residents, has resulted in thousands of infections and deaths and a high case fatality rate. To detect pre-symptomatic infections and identify infected workers, we performed weekly surveillance testing of staff at two LTCFs which revealed a large outbreak at one of the sites. We collected serum from staff member… Show more

Help me understand this report
View published versions

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
7
0

Year Published

2022
2022
2022
2022

Publication Types

Select...
1

Relationship

1
0

Authors

Journals

citations
Cited by 1 publication
(7 citation statements)
references
References 80 publications
0
7
0
Order By: Relevance
“…Neutralization assay. Standard plaque reduction neutralization test (PRNT) was performed as previously described [8]. Briefly, diluted sera were mixed with virus, incubated for one hour at 37°C, added to a Vero cell monolayer, incubated an additional hour at 37°C, then overlaid with tragacanth media and incubated for two days.…”
Section: Serum Collectionmentioning
confidence: 99%
See 4 more Smart Citations
“…Neutralization assay. Standard plaque reduction neutralization test (PRNT) was performed as previously described [8]. Briefly, diluted sera were mixed with virus, incubated for one hour at 37°C, added to a Vero cell monolayer, incubated an additional hour at 37°C, then overlaid with tragacanth media and incubated for two days.…”
Section: Serum Collectionmentioning
confidence: 99%
“…RBD and NP ELISA. Binding assays were performed as described previously [8]. Briefly, 96-well plates were coated with SARS-CoV-2 protein (RBD and NP from Sino Biological), blocked with non-fat dried milk, and diluted sera was added.…”
Section: Serum Collectionmentioning
confidence: 99%
See 3 more Smart Citations