Duranta Repens Linn. (Verbenaceae): A Comprehensive Review of Pharmacognostic, Ethnomedicinal, Pharmacological, and Phytochemical Aspects

Puri, Abhijeet

doi:10.22159/ajpcr.2018.v11i11.28509

Cited by 15 publications

(15 citation statements)

References 14 publications

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“…Literature studies by Ahmad et al [14] reported phytochemicals contain in the methanol extract of D. repens leaves that were collected around Mysore, India, included tannins, saponins, flavonoids, glycosides, steroids, and terpenoids. Phytochemical profiling of D. repens also revealed the presence of some imperative phytochemicals such as alkaloids, flavonoids, glycosides, phenolics, saponins, steroids, tannins, and terpenoids [1]. Phytochemical screening of the ethanol extract of D. erecta leaves and fruits from Ghana also indicated the presence of tannins, glycosides, saponins, flavonoids, triterpenoids, and sterol in ethanol extract leaves, both unripe and ripe fruit.…”

Section: Resultsmentioning

confidence: 94%

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The Phytochemical Screening Hexane and Methanol Extract of Sinyo Nakal (Duranta Repens)

Sugita

Amilia

Budi

et al. 2020

Asian J Pharm Clin Res

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Objective: Phytochemicals are naturally present in every part of plants range from leaves, stem bark, and fruits to roots. The use of plant-based medicine is popular among individuals and communities in developing countries. This study evaluated that the phytochemical profile of Duranta repens fruits was collected from Jombang, East Java, Indonesia. Methods: Air-dried D. repens fruits were macerated by n-hexane and methanol, a separate flask. n-Hexane extract, then underwent saponification to remove fat. Then, the unsaponifiable of n-hexane and methanol extract was tested through phytochemical screening, respectively. Results: The methanol extract showed the presence of alkaloids, flavonoids, tannins, and steroids, but the unsaponifiable fraction only contained steroids. The unsaponifiable fraction was found to be a mixture of hydrocarbons ranging from C13-C20, fatty acids (palmitic and linoleic acid), squalene, and Vitamin E. Conclusion: The phytochemical screening of the plant plays an important role for pharmaceutical studies especially discovering new potential drugs for the treatment of various diseases.

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Section: Resultsmentioning

confidence: 94%

“…1). The plants belong to Verbenaceae family which are herbs, shrubs, or trees comprising about 100 genus and 2600 species [1]. Around 35 Duranta species with evergreen bushes are spread over tropical and subtropical areas.…”

Section: Introductionmentioning

confidence: 99%

The Phytochemical Screening Hexane and Methanol Extract of Sinyo Nakal (Duranta Repens)

Sugita

Amilia

Budi

et al. 2020

Asian J Pharm Clin Res

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“…It is abundant in Asia, Africa, and South and Central America [9]. Previous studies have shown that it has been used for the management of headache, toothache, wound healing, liver protection, [8] and as diuretics [10]. Its anti-malarial activities have been reported [3].…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Screening and Antioxidant Potentials of Methanol Extract of Duranta erecta Leaves

Ugwu

Anosike

2020

AJRB

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Plant extracts that have antioxidant activities show promising effect in the management of many diseases initiated by oxidative stress. The present study evaluates the phytochemical composition and in vitro antioxidant potentials of methanol extract of Duranta erecta leaves. The extract was subjected to phytochemical screening, DPPH inhibition, ferric reducing antioxidant power (FRAP), nitric oxide determination, antioxidant vitamins and minerals composition analysis. All analyses were carried out using standard biochemical methods. The phytochemical evaluation of the plant extract showed the presence of flavonoids (24.20 ± 0.14 mg QE/g), Alkaloids (15.87 ± 1.71 mg/g), total phenol (12.73 ± 0.61 mg GAE/g), tannins (9.24 ± 0.03 mg TAE/g), terpenoids (8.90 ± 0.96 mg/g), steroids (2.65 ± 0.55 mg/g) and saponins (5.55 ± 0.76 mg/g). The in vitro antioxidant determination showed that the extract had antioxidant properties in a concentration dependent manner. The antioxidant property of the sample was compared to that of ascorbic acid (for DPPH and nitric oxide determination) and gallic acid (for FRAP) as standards. The antioxidant mineral composition of the extract revealed the presence of zinc (1.82 ± 0.03 mg/100g) and selenium (0.59 ± 0.04 mg/100g). The antioxidant vitamins composition of the extract showed moderate concentrations of vitamin C (0.35 ± 0.01 mg/100 g) and vitamin E (0.68 ± 0.07 mg/100g). The result of this study revealed that methanol extract of Duranta erecta leaves could be a good source of antioxidants.

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“…10 Prior studies have shown that it has been used for the management of headache, toothache, wound healing, liver protection, 11 and as diuretics. 12 Its anti-malarial activity have been reported. 12 Duranta erecta has been reported to be effective in the treatment of Urolithiasis in an animal model.…”

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confidence: 99%

“…12 Its anti-malarial activity have been reported. 12 Duranta erecta has been reported to be effective in the treatment of Urolithiasis in an animal model. 13 It has also been shown to be efficacious as an antiulcer agent and had anxiolytic effect in the experimental animal model.…”

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confidence: 99%

Effect of Methanol Leaf Extract of Duranta erecta in Rats Induced with Benign Prostatic Hyperplasia

2020

TJNPR

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The prostate gland is one of the parts that make up the male reproductive system. It is located at the base of the urinary bladder where it aids in the production of fluid that is alkaline in nature. This fluid helps to protect the sperm. 1 When there is an overgrowth of the prostate gland; it results in Benign Prostatic Hyperplasia (BPH). 2 BPH is one of the most frequent diseases in ageing men. Benign prostatic hyperplasia manifests in 30-40% of men within the age of 40 years, and its prevalence increases linearly to 70-80% in men older than 80 years. 3 BPH disease is depicted by a noncontrollable and rapid increase of the prostate epithelial cells and stromal cells, which results in enlargement of the prostate size. 4 As prostate increases, it narrows the urethra, thus decreasing the rate of urine outflow. The retention of urine in the bladder could lead to lower urinary tract symptoms (LUTS). 5 The disordered physiological processes associated with the disease are still unclear. However, several researchers have proposed that any of the following; oxidative stress, suppression of apoptosis and uncontrollable increase in cell proliferation play vital roles in the initiation and progression of BPH. 6

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Duranta Repens Linn. (Verbenaceae): A Comprehensive Review of Pharmacognostic, Ethnomedicinal, Pharmacological, and Phytochemical Aspects

Cited by 15 publications

References 14 publications

The Phytochemical Screening Hexane and Methanol Extract of Sinyo Nakal (Duranta Repens)

The Phytochemical Screening Hexane and Methanol Extract of Sinyo Nakal (Duranta Repens)

Phytochemical Screening and Antioxidant Potentials of Methanol Extract of Duranta erecta Leaves

Effect of Methanol Leaf Extract of Duranta erecta in Rats Induced with Benign Prostatic Hyperplasia

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