Duration and quality of sleep during pregnancy are associated with preterm birth and small for gestational age: A prospective study

Abstract

Objective: To explore the associations of duration and quality of sleep during pregnancy with preterm birth and small for gestational age (SGA).Methods: A prospective study was carried out on 1082 healthy women with singleton pregnancies from Chengdu, China. Self-report questionnaires, including duration and quality of sleep and other information, were administered at 8-12, 24-28, and 32-36 weeks of pregnancy. Data on gestational age and weight and length of the neonates were recorded after delivery. After controlling the potential confounders, a multivariable logistic regression model was performed to evaluate whether duration and quality of sleep were associated with preterm birth and SGA.Results: Participants with short duration of sleep during the third trimester were more likely to report preterm birth (odds ratio [OR] 2.16, 95% confidence interval [CI] 1.26-4.81) and SGA (OR 2.67, 95% CI 1.18-6.54). Participants with poor quality of sleep during the third trimester were at high risk for preterm birth (OR 2.26,) and SGA (OR 2.08,. Conclusion:Short duration and poor quality of sleep during pregnancy are associated with an increased risk of preterm birth and SGA. Sleep characteristics should be assessed during prenatal evaluations to decrease adverse maternal and fetal outcomes.

Maternal sleep during pregnancy and adverse pregnancy outcomes: A systematic review and meta‐analysis

“…Figure 1 shows a flowchart outlining the selection of eligible literature. There were 5,246 articles initially identified, after removing duplicates and double assessment, 41 of which were ultimately included in the meta‐analysis 8 , 14 , 15 , 21 , 22 , 23 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 . These studies took place mainly in the USA ( n = 13) 8 , 31 , 32 , 33 , 34 , 35 , 38 , 39 , ...…”

“…These studies took place mainly in the USA ( n = 13) 8 , 31 , 32 , 33 , 34 , 35 , 38 , 39 , 47 , 49 , 50 , 58 , 59 . Most studies were cohorts ( n = 32) 8 , 14 , 15 , 21 , 22 , 23 , 30 , 31 , 32 , 33 , 34 , 36 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 58 , 59 , 62 , whereas there were seven case–control studies 35 , 37 , 55 , 56 , 57 , 60 , 61 and two cross‐sectional studies ...…”

“…A total of 16 studies ( n = 24, 58.8%) reported data for the second trimester. The measurement of sleep time included a questionnaire ( n = 28) 8 , 14 , 15 , 21 , 22 , 29 , 31 , 33 , 34 , 35 , 36 , 37 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 48 , 49 , 50 , 54 , 56 , 59 , 60 , 61 , 63 , PSQI ( n = 8) 23 , 30 , 51 , 53 , 55 , 57 , 58 , 62 , structured interview ( n = 1) 47 , monitor ( n = 2) 38 , 39 , sleep log ( n = 1) 32 and one study did not report 52 . Notably, studies were published from 2004 to 2021.…”

“…Figure 1 shows a flowchart outlining the selection of eligible literature. There were 5,246 articles initially identified, after removing duplicates and double assessment, 41 of which were ultimately included in the meta‐analysis 8,14,15,21–23,29–63 . These studies took place mainly in the USA ( n = 13) 8,31–35,38,39,47,49,50,58,59 .…”

“…These studies took place mainly in the USA ( n = 13) 8,31–35,38,39,47,49,50,58,59 . Most studies were cohorts ( n = 32) 8,14,15,21–23,30–34,36,38–54,58,59,62 , whereas there were seven case–control studies 35,37,55–57,60,61 and two cross‐sectional studies 29,63 . A total of 16 studies ( n = 24, 58.8%) reported data for the second trimester.…”