Dutch multicenter experience using the STENTYS Xposition S self‐apposing stent in complex coronary lesions

Abstract

Objectives The aim is to assess the experience in the Netherlands using the Xposition S self‐apposing stent in complex coronary lesions in clinical practice. Background Treatment of complex coronary lesions could be accompanied with stent sizing difficulties and complications, particularly due to vessel overdilation or stent underexpansion. The self‐apposing feature of the Xposition S stent (STENTYS, Paris, France) supports good strut apposition in complex anatomies and allows for an increase in diameter after implantation. Methods In this real‐world registry, data from patients treated with Xposition S in four Dutch clinical sites were prospectively collected and analyzed. Any patient suitable for implantation with Xposition S according to current recommendations was enrolled. Primary endpoint was major adverse cardiac events (MACE) at 1 year. Results Between 2015 and 2018, data from 251 patients were collected. Clinical presentation was an acute coronary syndrome in majority of the patients (76.9%). Main angiographic indications were lesions in aneurysmatic or ectatic vessels (32.3%), thrombus containing lesions (13.1%), and bifurcation/left main stenosis (10.4%). Most of the target lesions (TLs) were classified as AHA/ACC Type C (53.6%). Despite lesion complexity, device was successfully implanted at TL in 96.8%. MACE rate, reported on patients having completed 1‐year follow‐up (n = 203), was 6.6%, with low rate of definite/probable stent thrombosis (1.0%). Conclusions In clinical practice of several Dutch sites, STENTYS Xposition S showed good procedural results and low 1‐year clinical events rate, despite complex coronary anatomy.