Dutch national guidelines for locally recurrent rectal cancer

Piqeur, Floor; Creemers, Davy M.J.; Banken, Evi; Coolen, Liën; Tanis, Pieter J.; Maas, Monique; Roef, Mark; Marijnen, Corrie A.M.; van Hellemond, Irene E.G.; Nederend, Joost; Rutten, Harm J.T.; Peulen, Heike M.U.; Burger, Jacobus W.A.

doi:10.1016/j.ctrv.2024.102736

Cancer Treatment Reviews

2024

DOI: 10.1016/j.ctrv.2024.102736

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Dutch national guidelines for locally recurrent rectal cancer

Floor Piqeur,

Davy M.J. Creemers,

Evi Banken

et al.

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2024

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Cited by 2 publications

References 72 publications

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Analysis of re-recurrent rectal cancer after curative treatment of locally recurrent rectal cancer

Piqeur,

Coolen,

Nordkamp

et al. 2024

Radiotherapy and Oncology

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Analysis of re-recurrent rectal cancer after curative treatment of locally recurrent rectal cancer

Piqeur,

Coolen,

Nordkamp

et al. 2024

Radiotherapy and Oncology

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Current Management of Locally Recurrent Rectal Cancer

Coco,

Rizzo,

Amodio

et al. 2024

Cancers

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Locally recurrent rectal cancer (LRRC), which occurs in 6–12% of patients previously treated with surgery, with or without pre-operative chemoradiation therapy, represents a complex and heterogeneous disease profoundly affecting the patient’s quality of life (QoL) and long-term survival. Its management usually requires a multidisciplinary approach, to evaluate the several aspects of a LRRC, such as resectability or the best approach to reduce symptoms. Surgical treatment is more complex and usually needs high-volume centers to obtain a higher rate of radical (R0) resections and to reduce the rate of postoperative complications. Multiple factors related to the patient, to the primary tumor, and to the surgery for the primary tumor contribute to the development of local recurrence. Accurate pre-treatment staging of the recurrence is essential, and several classification systems are currently used for this purpose. Achieving an R0 resection through radical surgery remains the most critical factor for a favorable oncologic outcome, although both chemotherapy and radiotherapy play a significant role in facilitating this goal. If a R0 resection of a LRRC is not feasible, palliative treatment is mandatory to reduce the LRRC-related symptoms, especially pain, minimizing the effect of the recurrence on the QoL of the patients. The aim of this manuscript is to provide a comprehensive narrative review of the literature regarding the management of LRRC.

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Dutch national guidelines for locally recurrent rectal cancer

Cited by 2 publications

References 72 publications

Analysis of re-recurrent rectal cancer after curative treatment of locally recurrent rectal cancer

Analysis of re-recurrent rectal cancer after curative treatment of locally recurrent rectal cancer

Current Management of Locally Recurrent Rectal Cancer

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