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Abstract

Objectives: Over the past 2 decades, significant advances have been made in the management of infections after transplant; however, transplant recipients are still at high risk of infectious complications. This study aimed to evaluate the prevalence of bacterial infections and antimicrobial resistance patterns in kidney transplant recipients. Conclusions:Because of the high prevalence of infection among transplant patients, infection prevention should receive more attention, and antibiotic susceptibility should be determined before treatment. Key words: Antibiotic resistance, Coagulase-negative Staphylococcus, Escherichia coli, Renal transplantation IntroductionOne of the primary and major aims in organ transplant is the effective prevention and treatment of infections. During the previous 2 decades, significant advances have been made in the management of infection after transplant. However, transplant recipients are still at high risk of infectious complications, due to the surgical interventions, immunosuppressive therapy, and exposure to the environment. 1 In transplant patients, there are generally 3 times the incidences of infections after transplant, which are usually divided as those that occur during the first month posttransplant, those that occur 2 to 6 months posttransplant, and those that occur more than 6 months posttransplant.Most infections in the first month, especially the first 2 weeks after transplant, occur in relation to technical and operative factors. These infections include pneumonia, wound infection, those related to intravenous catheter, and urinary tract infection. 2 In addition are complications that result from infections causing the death of organ transplant recipients and in some cases organ transplant rejections, especially infections that are caused by drug-resistant bacteria. [2][3][4] Urinary tract infections are the most common problem after kidney transplant. Almost 70% of these infections are caused by gramnegative bacteria, especially Escherichia coli and Klebsiella pneumoniae. 4 In addition to gram-negative bacteria, some gram-positive bacteria, including

What Are the Burden, Causes, and Costs of Early Hospital Readmissions After Kidney Transplantation?

“…In addition, careful considerations of the interaction between antibiotic medication and immunosuppression and infection with resistant bacteria are always imperative when deciding on a prophylactic measure. 19 …”