Dynamic biomechanical characterization of colon tissue according to anatomical factors

Massalou, Damien; Masson, Catherine; Foti, Pauline; Afquir, Sanae; Baqué, Patrick; Berdah, Stéphane; Bège, Thierry

doi:10.1016/j.jbiomech.2016.10.023

Cited by 17 publications

(11 citation statements)

References 23 publications

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“…In a previous study, we highlighted the influence of the location on the colon frame on its mechanical response under uniaxial traction, until rupture [9]. This result was also shown in Howes' dynamic bi-axial colon stress [10].…”

Section: Introductionsupporting

confidence: 57%

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Influence of gender, age, shelf-life, and conservation method on the biomechanical behavior of colon tissue under dynamic solicitation

Massalou

Masson

Afquir

et al. 2019

Clinical Biomechanics

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Background: Data from biomechanical tissue sample studies of the human digestive tract are highly variable. The aim of this study was to investigate 4 factors which could modify the mechanical response of human colonic specimens placed under dynamic solicitation until tissue rupture: gender, age, shelf-life and conservation method.Methods: We performed uniaxial dynamic tests of human colonic specimens. Specimens were taken according to three different protocols: refrigerated cadavers without embalming, embalmed cadavers and fresh colonic tissue. A total of 143 specimens were subjected to tensile tests, at a speed of 1 m s -1 .Findings: Young's modulus of the different conservation protocols are as follows: embalmed, 3.08 +/-1.99; fresh, 2.97 +/-2.59; and refrigerated 3.17 +/-2.05. The type of conservation does not modify the stiffness of the tissue (p = 0.26) but does modify the stress necessary for rupture (p < 0.001) and the strain required to obtain lesions of the outer layer and the inner layer (p < 0.001 and p < 0.05, respectively). Gender is also a factor responsible for a change in the mechanical response of the colon. The age of the subjects and the shelf-life of the bodies did not represent factors influencing the mechanical behavior of the colon (p > 0.05). Interpretation:The mechanical response of the colon tissue showed a biphasic injury process depending on gender and method of preservation. The age and shelf-life of anatomical subjects do not alter the mechanical response of the colon.

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Section: Introductionsupporting

confidence: 57%

“…Experimental characterization of the mechanical behavior of the colon was carried out by performing uniaxial tensile tests under a dynamic load of m s -1 . The modalities of the traction protocol and preconditioning have been detailed previously by our team [9].…”

Section: Experimental Conditionsmentioning

confidence: 99%

Influence of gender, age, shelf-life, and conservation method on the biomechanical behavior of colon tissue under dynamic solicitation

Massalou

Masson

Afquir

et al. 2019

Clinical Biomechanics

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“…where X refers to the collagen fiber contribution, and is defined as the sum of the contributions of each collagen family of fibrils, so that: 7) where the average of the n contributions is denoted by the notation 〈⋅〉, g corresponds to the number of families of collagen fibers, according to experimental results, N=2.…”

Section: Microstructural Models (Mfm and Mfb)mentioning

confidence: 99%

“…Among the published works, a few reports can be found of tensile tests performed on human colon tissue. Ergov et al ( 2002) [6] and more recently Massalou et al (2016) [7] present different results corresponding to uniaxial dynamic tensile tests. However, there are several reports of biomechanical characterization of colon tissue from common laboratory animals using different mechanical tests and constitutive models: tests of compression in goat colon [8], tensile tests and a constitutive model for pig colon tissue [9][10][11], extension-inflation tests and a constitutive model for pig colon tissue [12] and tensile tests and biomechanical characterization of rat colon [13,14].…”

Section: Introductionmentioning

confidence: 99%

A comparative study of hyperelastic constitutive models for colonic tissue fitted to multiaxial experimental testing

Puértolas¹,

Peña²,

Herrera³

et al. 2020

Journal of the Mechanical Behavior of Biomedical Materials

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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“…Considering the difficulties involved in gripping the bowel, the biggest challenge of mobile devices is to design an effective propelling mechanism. These difficulties include the bowel’s viscoelastic properties 20–22 and its non-uniform diameter, but most of all, its slippery surface due to the presence of intestinal mucosa. 19,23–25 De Simone and Luongo 26 studied a non-linear model of a viscoelastic balloon compressed between two rigid plates concluding that, in the majority of the biomedical applications where the strain is not too high, the complex non-linear constitutive models are unnecessary.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the ‘Endoworm’ prototype’s ability to grip the bowel in in vitro and ex vivo models

Tobella

Pons-Beltrán

Santonja

et al. 2020

Proc Inst Mech Eng H

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Access to the small bowel by means of an enteroscope is difficult, even using current devices such as single-balloon or double-balloon enteroscopes. Exploration time and patient discomfort are the main drawbacks. The prototype ‘Endoworm’ analysed in this paper is based on a pneumatic translation system that, gripping the bowel, enables the endoscope to move forward while the bowel slides back over its most proximal part. The grip capacity is related to the pressure inside the balloon, which depends on the insufflate volume of air. Different materials were used as in vitro and ex vivo models: rigid polymethyl methacrylate, flexible silicone, polyester urethane and ex vivo pig small bowel. On measuring the pressure–volume relationship, we found that it depended on the elastic properties of the lumen and that the frictional force depended on the air pressure inside the balloons and the lumen’s elastic properties. In the presence of a lubricant, the grip on the simulated intestinal lumens was drastically reduced, as was the influence of the lumen’s properties. This paper focuses on the Endoworm’s ability to grip the bowel, which is crucial to achieving effective endoscope forward advance and bowel folding.

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Dynamic biomechanical characterization of colon tissue according to anatomical factors

Cited by 17 publications

References 23 publications

Influence of gender, age, shelf-life, and conservation method on the biomechanical behavior of colon tissue under dynamic solicitation

Influence of gender, age, shelf-life, and conservation method on the biomechanical behavior of colon tissue under dynamic solicitation

A comparative study of hyperelastic constitutive models for colonic tissue fitted to multiaxial experimental testing

Analysis of the ‘Endoworm’ prototype’s ability to grip the bowel in in vitro and ex vivo models

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