Dynamic bone scintigraphy in osteochondritis dissecans

Abstract

We report a retrospective study of eighteen patients with pain in the knee or ankle, eleven of whom had osteochondritis dissecans. In these patients the bone-flow time-activity curves were observed after an intravenous injection of a bolus of 99mTc MDP. The curves varied according to the severity of the clinical signs and symptoms. The diagnosis rate was 29% with static scintigraphy and this improved to 57% when dynamic flow studies were used. A positive pattern in the dynamic study together with radiographs and static scintigraphs raised the diagnosis rate to 100%; the sensitivity was 90%. These preliminary results show that dynamic bone scintigraphy holds promise as a technique for identification and management of this condition.

Prospective study on diagnostic strategies in osteochondral lesions of the talus

“…5,6 The frequent absence of radiological changes has led to the use of more sensitive methods of detection. 7 While some authors prefer additional radiographs such as mortise views with a 4 cm heel-rise, the lack of precise localisation and extent of the lesion remains a problem. 8,9 Therefore, others prefer CT, 10 MRI, [11][12][13] or diagnostic arthroscopy.…”

Diagnostic imaging modalities for osteochondral defects of the talus

“…The standard radiographs may show an area of detached bone surrounded by radiolucency but initially the damage may be too small to be visualized [21]. The frequent absence of radiological changes has led to the use of more sensitive methods [17]. Berndt and Harty provided great insight into the pathophysiology and anatomy and were, in 1959, the first to make a classification of OCDs of the talus.…”

Advanced Magnetic Resonance Imaging and Molecular Imaging of the Painful Knee

“…Whereas other diagnostic modalities, such as MRI or radiographs alone, lack accuracy in predicting healing in JOCD patients, bone blood flow measurements and radiographs together dramatically improve diagnostic accuracy. 32 In addition, relative blood flow changes between the focal lesion and the surrounding healthy bone are highly correlated with clinical outcomes. 33 However, because of concerns of exposure to ionizing radiation and the potential toxicity of exogenous contrast agents, the application of these methods for assessing bone perfusion is limited.…”