Dynamic Combinatorial Chemistry 2009
DOI: 10.1002/9780470551554.ch1
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Dynamic Combinatorial Chemistry: An Introduction

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Cited by 6 publications
(5 citation statements)
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References 89 publications
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“…Dynamic Covalent Bonding (DCB) can be used to exchange molecular components to reach the thermodynamic minima of a system. [1][2][3][4][5][6] In recent decades, DCB has been explored due to applicability in supramolecular chemistry. [7][8][9][10] For example, DCB is useful in creating new molecular receptors, protein ligands and sensors.…”
Section: Introductionmentioning
confidence: 99%
“…Dynamic Covalent Bonding (DCB) can be used to exchange molecular components to reach the thermodynamic minima of a system. [1][2][3][4][5][6] In recent decades, DCB has been explored due to applicability in supramolecular chemistry. [7][8][9][10] For example, DCB is useful in creating new molecular receptors, protein ligands and sensors.…”
Section: Introductionmentioning
confidence: 99%
“…The challenge is now to stabilize the desired product and thus to "amplify it". [5][6][7][8] In macrocycles, such a stabilization can be achieved by incorporation of a matching guest, but the reaction can also be seen from the perspective of the guest: the guest will interact with all members of the mixture and besides stabilizing the final macrocycle it will also assemble building blocks of the macrocycle, thus bringing them together. Thus, the guest acts as a template (Scheme 1).…”
Section: Introductionmentioning
confidence: 99%
“…Dynamic Combinatorial Chemistry (DCC) was originally introduced as a method to mimic evolution in the identification of small molecules with novel properties by allowing binding-induced selection (or, in other cases, self-selection) to act on an equilibrating system of structures. 1, 2 This field has grown to encompass a broad range of studies known as “dynamic covalent chemistry”, 3 “systems chemistry”, 4 or “constitutional dynamic chemistry”. 5 Systems employing dynamic exchange of covalent bonds have enabled the discovery of polymers with novel materials properties, 6, 7, 8 new molecular architectures, 9 highly selective host-guest systems, and new ligands for binding macromolecules.…”
Section: Introductionmentioning
confidence: 99%