Dynamic content changes of cordycepin and adenosine and transcriptome in Cordyceps kyushuensis Kob at different fermentation stages

Abstract

20% (w/w) Astragali radix was added to the rice medium to cultivate C. kyushuensis Kob. The fermentation product was collected at mycelium stage, coloring stage, stromata-forming initial stage and fruiting body stage of C. kyushuensis Kob. The dynamic content changes of cordycepin and adenosine were detected at different fermentation stages. In the rice medium with Astragalus radix, both cordycepin and adenosine reached the highest content value on the 30th day of fermentation, 17.31 mg/g and 0.94 mg/g, respectively, which were 8.6 times and 2.0 times of that in rice medium at the same stage. At the same time, transcriptomics technology was used to analyze C. kyushuensis Kob during these four periods.

Morphology and Phylogeny Reveal Five Novel Species in the Genus Cordyceps (Cordycipitaceae, Hypocreales) From Yunnan, China

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Systematic analyses with genomic and metabolomic insights reveal a new species, Ophiocordyceps indica sp. nov. from treeline area of Indian Western Himalayan region

“…Ophiocordyceps sinensis is commonly recognized as “soft gold” (Woodhouse et al, 2014 ), “fungal gold” (Panicker, 2017 ), or “organic gold” (Pouliot et al, 2018 ), and reported to be even pricier than gold (Li et al, 2015 ). Owing to the findings of bioactive components in relation to anti-aging, anti-tumor, antioxidant, anti-inflammatory, and immuno-modulatory activities, Ophiocordyceps has attracted substantial interest in the modern medicine sector, in addition to its traditional consumption (Lou et al, 2019 ; Li Y. et al, 2021 ; Zhang et al, 2021 ). There was a 900% rise in its price between 1998 and 2008, and top-quality Ophiocordyceps were sold at $145,000/kg (Li X. et al, 2019 ; Li Y. et al, 2021 ).…”

Genomic Comparative Analysis of Cordyceps pseudotenuipes with Other Species from Cordyceps

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