With the rapidly development of global military, missiles play an increasingly important role in modern war. The realization of precise guidance for missiles has become an important problem to be solved at present, and the seeker is an important equipment to realize precise guidance.The traditional gimbal seeker has many disadvantages such as large volume, high cost and complex structure, so the strapdown seeker appears. Although the strapdown seeker can effectively solve the problems above,there are problems such as high noise, attitude coupling, phase matching, etc.So, strapdown seeker requires higher estimation algorithm than traditional gimbal seeker. In order to improve the filtering accuracy, this paper adds an adaptive link to the unscented Kalman filter to form an adaptive unscented Kalman filter.Finally, through simulation and comparison, it is found that the filtering accuracy after adding adaptation is a little higher than that before adding adaptation.