Due to uncertainty and dynamic characteristics from intermittent energy and load demand response (DR), it brings great challenge to optimal operation of hybrid energy system. This paper proposes an event-triggered multi-agent coordinated optimization strategy with two-layered architecture. Firstly, price-bidding based DR model is proposed with different stakeholders, and it also deduces optimal bidding price with Nash equilibrium theory. Then, four agents are designed to control different kind of energy resources, Agent 1 mainly analyzes the uncertainty or randomness caused by intermittent power, Agent 2 takes charge of dynamic economic dispatch (DED) within thermal units, Agent 3 manages the optimal scheduling of energy storage, and Agent 4 mainly undertakes load shifting strategy from consumers. In the upperlayer level, all agents coordinate together to ensure the stability of hybrid energy system with event-triggered mechanism, the intelligent control approach mainly depends on switching on/off power generators or curtailing system load, and consensus algorithm is utilized to optimize subsystem problem in lowerlayer level. Furthermore, simulation results can further verify the efficiency of proposed method, and it also reveals that eventtriggered multi-agent optimization strategy can be a promising way for solving hybrid energy system problem. Index Terms-event-triggered, coordinated optimization, demand response, intelligent control, hybrid energy system.