2023
DOI: 10.1002/btpr.3411
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Dynamic flux balance analysis of 1,3‐propanediol production by clostridium butyricum fermentation

Duo‐Tao Pan,
Pan Wang,
Xiao‐Li Wang
et al.

Abstract: To study the relationship between the yield of 1,3‐propanediol (1,3‐PDO) and the flux change of the Clostridium butyricum metabolic pathway, an optimized calculation method based on dynamic flux balance analysis was used by combining genome‐scale flux balance analysis with a kinetic model. A more comprehensive and extensive metabolic pathway was obtained by optimization calculations. The primary extended branches include: the dihydroxyacetone node, which enters the pentose phosphate pathway; the α‐oxoglutarate… Show more

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