Dynamic Left Ventricular Outflow Tract Obstruction Induced by Exercise

Beta-blocker therapy for dynamic left ventricular outflow tract obstruction induced by exercise

“…A subgroup of these patients could develop left ventricular outflow tract obstruction during exercise and become a cause of symptoms [1,2,27]. Recently, it has been described that dynamic intraventricular obstruction appeared in 18 of 134 patients (13.4%), in the absence of hypertrophic obstructive cardiomyopathy or significant valvular heart disease, with In the present study, 15 of 78 patients without evidence of ischemia developed DLVOTO induced by exercise.…”

“…However, another potential cause of angina or breathlessness has recently been suggested [1][2][3]: dynamic left ventricular outflow tract obstruction (DLVOTO) induced by exercise must be considered as a possible cause of symptoms in patients without evidence of ischemia.…”

Dobutamine Stress Echocardiography Identifies Patients with Angina and Dynamic Left Ventricular Outflow Obstruction in Physiological Exercise

“…[6][7][8] However, little evidence exists about the reproducibility of this phenomenon during exercise and dobutamine stress testing in patients with effort angina. 11,12 In our series, the onset of DLVOTO during dobutamine stress testing in 48.7% of patients was similar to the 38% seen in a series of 52 patients with angina and normal coronary arteries.…”

Baseline Predictors of Dynamic Obstruction During Stress Echocardiogram: The Importance of Ventricular Anatomy and Body Surface Area

“…As previously published by our group, taking a similar cutoff to consider a dynamic gradient as significant, it is observed that DLVO onset both during stress with dobutamine and post‐effort is related with echocardiographic parameters of left ventricular anatomy 2–4 . However, in these series, which also include relative wall thickness in the analysis, the main related factor and independent predictor of the onset of dynamic obstruction is the diameter of the left ventricular outflow tract (LVOT) adjusted to body surface area.…”