Dynamic Magnetic Resonance Imaging of Femoral Head Perfusion in Femoral Neck Fracture

Hirata, Tetsuo; Konishiike, T.; Kawai, Akira; Satô, Tôru; Inoue, Hajime

doi:10.1097/00003086-200112000-00034

Cited by 44 publications

(25 citation statements)

References 16 publications

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“…To evaluate femoral head perfusion, dynamic MRI was carried out according to the method proposed by Konishiike et al [22,23]. A 1.0-Tesla superconducting scanner was used (Philips Ò , Eindhoven, the Netherlands) with a two-dimensional fast low-angle shot with fat saturation.…”

Section: Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%

Intramedullary femoral nailing through the trochanteric fossa versus greater trochanter tip: a randomized controlled study with in-depth functional outcome results

Moein

Duis

Oey

et al. 2011

Eur J Trauma Emerg Surg

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Section: Magnetic Resonance Imaging (Mri)mentioning

confidence: 99%

Intramedullary femoral nailing through the trochanteric fossa versus greater trochanter tip: a randomized controlled study with in-depth functional outcome results

Moein

Duis

Oey

et al. 2011

Eur J Trauma Emerg Surg

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“…However, despite its use for the diagnosis of carpal bone nonunions and spinal pseudarthroses [22][23][24][25], MRI has not been useful in evaluating delayed fracture healing in the long bones. Scintigraphic studies with 99m Tc-labeled compounds have also been used to evaluate carpal bones [26,27]; however, multiple studies have demonstrated no significant differences in tracer uptake between tibia fractures that heal normally and those that form nonunions [28,29].…”

Section: Introductionmentioning

confidence: 99%

The use of 18F-fluoride and 18F-FDG PET scans to assess fracture healing in a rat femur model

Hsu

Feeley

Krenek

et al. 2007

Eur J Nucl Med Mol Imaging

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Purpose-Currently available diagnostic techniques can be unreliable in the diagnosis of delayed fracture healing in certain clinical situations, which can lead to increased complication rates and costs to the health care system. This study sought to determine the utility of positron emission tomography (PET) scanning with 18 F-fluoride ion, which localizes in regions of high osteoblastic activity, and 18 F-fluorodeoxyglucose (FDG), an indicator of cellular glucose metabolism, in assessing bone healing in a rat femur fracture model. Methods-Fractureswere created in the femurs of immuno-competent rats. Animals in group I had a fracture produced via a manual three-point bending technique. Group II animals underwent a femoral osteotomy with placement of a 2-mm silastic spacer at the fracture site. Fracture healing was assessed with plain radiographs, 18 F-fluoride, and 18 F-FDG PET scans at 1, 2, 3, and 4-week time points after surgery. Femoral specimens were harvested for histologic analysis and manual testing of torsional and bending strength 4 weeks after surgery.Results-All fractures in group I revealed abundant callus formation and bone healing, while none of the nonunion femurs were healed via assessment with manual palpation, radiographic, and histologic evaluation at the 4-week time point. 18 F-fluoride PET images of group I femurs at successive 1-week intervals revealed progressively increased signal uptake at the union site during fracture repair. In contrast, minimal tracer uptake was seen at the fracture sites in group II at all time points after surgery. Data analysis revealed statistically significant differences in mean signal intensity between groups I and II at each weekly interval. No significant differences between the two groups were seen using 18 F-FDG PET imaging at any time point.Conclusion-This study suggests that 18 F-fluoride PET imaging, which is an indicator of osteoblastic activity in vivo, can identify fracture nonunions at an early time point and may have a role in the assessment of longitudinal fracture healing. PET scans using 18 F-FDG were not helpful in differentiating metabolic activity between successful and delayed bone healing.

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“…1,2 The risk of this complication directly affects the selection of surgical options for femoral neck fractures: internal fixation or arthroplasty.…”

Section: Introductionmentioning

confidence: 99%

Prediction of Avascular Necrosis of the Femoral Head by Measuring Intramedullary Oxygen Tension After Femoral Neck Fracture

Watanabe

Terashima

Takenaka

et al. 2007

Journal of Orthopaedic Trauma

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Dynamic Magnetic Resonance Imaging of Femoral Head Perfusion in Femoral Neck Fracture

Cited by 44 publications

References 16 publications

Intramedullary femoral nailing through the trochanteric fossa versus greater trochanter tip: a randomized controlled study with in-depth functional outcome results

Intramedullary femoral nailing through the trochanteric fossa versus greater trochanter tip: a randomized controlled study with in-depth functional outcome results

The use of 18F-fluoride and 18F-FDG PET scans to assess fracture healing in a rat femur model

Prediction of Avascular Necrosis of the Femoral Head by Measuring Intramedullary Oxygen Tension After Femoral Neck Fracture

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