Dynamic nanosurface reconfiguration by host–guest supramolecular interactions

Abstract

The dynamic functionalization of nanoparticle surface with biocompatible coatings is a critical step towards the development of functional nano-sized systems. While covalent approaches have been broadly exploited in the stabilization...

Supramolecular Click Chemistry for Surface Modification of Quantum Dots Mediated by Cucurbit[7]uril

“…For example, Velders and co-workers used thiolated β-CD as an Au NP surface-bound host, capable of complexing ferrocene and adamantyl guests, to sense horseradish peroxidase via oxidation of the ferrocene guest and subsequent decomplexation from the nanoparticle surface . Likewise, Montenegro et al recently applied a similar scheme using multivalent adamantyl anchors to-modify the surface of Au NPs inside cells with pegylated peptides . Ravoo and co-workers have exploited thiolated β-CD or carboxylate-modified β-CD to link together Au NPs, iron oxide NPs and LiYF 4 upconverting NPs with a photoswitchable azobenzene guest, to create a modular system capable of reversible self-assembly. , Others have also exploited this approach for patchy gold-on-polystyrene microparticles .…”