2003
DOI: 10.1016/s0098-1354(02)00116-3
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Dynamic optimization of batch processes

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Cited by 365 publications
(11 citation statements)
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“…The original formulation for the run-to-run control applied to insulin bolus dosing and timing is described in Reference [19]. It is based on the application of a constraint control scheme in the run-to-run framework to optimize the operation of batch processes in the chemical industry [21,22].…”
Section: Run-to-run Algorithmmentioning
confidence: 99%
“…The original formulation for the run-to-run control applied to insulin bolus dosing and timing is described in Reference [19]. It is based on the application of a constraint control scheme in the run-to-run framework to optimize the operation of batch processes in the chemical industry [21,22].…”
Section: Run-to-run Algorithmmentioning
confidence: 99%
“…Such trajectories can be obtained in several ways, based on: (i) prior physical or heuristic knowledge of the plant, 61 (ii) some empirical rules, or (iii) optimization approaches that exploit a mathematical model of the plant. 62,63 When optimization-based approaches are applied over nonlinear/complex dynamics, computational expensive procedures are employed offline to obtain sub-optimal (or, if possible, optimal) solutions to the given problem. This work relies on this latter approach, which is discussed in MPC formulation for LTV systems section.…”
Section: This Work Uses the Euclidean Norm As The Distance Function Dmentioning
confidence: 99%
“…Run-to-run optimization as defined above is a broad category that can be further classified based on how the optimization updates are implemented [24]. Model-explicit optimization uses a model of the system dynamics to compute the local gradient based on current measurements [24,25]. In Ref.…”
Section: Run-to-run Controlmentioning
confidence: 99%
“…References [24,25], and [27] suggest that I be chosen as constructs or parameters with target values that are necessary for optimality, e.g., I as the terminal values for output levels which are constrained to be 0 at t final for an optimal solution. This configuration is designed such that as I is regulated toward its target values, the overall system will then converge to the optimal solution.…”
Section: Run-to-run Controlmentioning
confidence: 99%
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