Dynamic range extension of SiPM detectors with the time-gated operation

Figueras, E. Vilella; Diéguez, Ángel

doi:10.1364/oe.22.012007

Cited by 8 publications

(4 citation statements)

References 14 publications

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“…The setup built for both fluorescence methods is the same. To perform the measurements, the LED light is pulsed, and time gating is applied before the failing edge of the excitation [ 48 , 49 ]. For intensity measurements, the light measured after the LED is turned off is measured, thus detecting a fluorophore or background.…”

Section: Methodsmentioning

confidence: 99%

Fluorescence Multi-Detection Device Using a Lensless Matrix Addressable microLED Array

Moro,

Canals,

Moreno

et al. 2024

Biosensors

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A Point-of-Care system for molecular diagnosis (PoC-MD) is described, combining GaN and CMOS chips. The device is a micro-system for fluorescence measurements, capable of analyzing both intensity and lifetime. It consists of a hybrid micro-structure based on a 32 × 32 matrix addressable GaN microLED array, with square LEDs of 50 µm edge length and 100 µm pitch, with an underneath wire bonded custom chip integrating their drivers and placed face-to-face to an array of 16x16 single-photon avalanche diodes (SPADs) CMOS. This approach replaces instrumentation based on lasers, bulky optical components, and discrete electronics with a full hybrid micro-system, enabling measurements on 32 × 32 spots. The reported system is suitable for long lifetime (>10 ns) fluorophores with a limit of detection ~1/4 µM. Proof-of-concept measurements of streptavidin conjugate Qdot™ 605 and Amino PEG Qdot™ 705 are demonstrated, along with the device ability to detect both fluorophores in the same measurement.

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Section: Methodsmentioning

confidence: 99%

Fluorescence Multi-Detection Device Using a Lensless Matrix Addressable microLED Array

Moro,

Canals,

Moreno

et al. 2024

Biosensors

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show abstract

“…38 To boost MPPC applications in the high-speed quantum information system, baseline corrections 39 and sinusoidal gating techniques 40 have been propounded, giving MPPC the prospect of running at a high repetition rate. The dynamic range is governed by the number of MPPC pixels and can be extended by time-gated mode 41 or by nonlinear calibration of the MPPC response. 42 Furthermore, in pursuit of extending the spectral response range of the MPPC, researchers have conceived several novel solutions.…”

Section: Detection Performance Improvementmentioning

confidence: 99%

Quantum characteristics and applications of multi‐pixel photon counter

Cai

Chen

et al. 2021

Micro & Optical Tech Letters

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In this invited paper, we present an overview of the multi-pixel photon counter (MPPC), which is a kind of spatial-multiplexed photon-number-resolving detector. We review the operation principles of MPPC, its characterization via quantum detector tomography, and the applications of this detector in research fields such as quantum information, remote sensing and biological medicine. Finally, we discuss the current progress on the improvement of MPPC.

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“…In the case of advanced researches, weak-light detection at a single photon level is often required, such as fluorescence due to a relatively small number of atoms and molecules. Among various highly sensitive photon sensors with single-photon detection capability, silicon photomultipliers (SiPMs) have recently emerged as high-performance alternative, with significant development and expanding list of applications [1,2,3,4,5,6]. Avalanche photodiodes (APDs) have high quantum efficiency but too much noise for low photon counts, photomultiplier tubes (PMTs) have low noise but low quantum efficiency.…”

Section: Introductionmentioning

confidence: 99%

High-sensitivity low-noise photodetector using large-area silicon photomultiplier

Masuda¹,

Hiramoto²,

Ang³

et al. 2022

Preprint

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The application of silicon photomultiplier (SiPM) technology for weak-light detection at a single photon level has expanded thanks to its better photon detection efficiency in comparison to a conventional photomultiplier tube (PMT). SiPMs with large detection area have recently become commercially available, enabling applications where the photon flux is low both temporarily and spatially. On the other hand, several drawbacks exist in the usage of SiPMs such as a higher dark count rate, many readout channels, slow response time, and optical crosstalk; therefore, users need to carefully consider the trade-offs. This work presents a SiPM-embedded compact largearea photon detection module. Various techniques are adopted to overcome the disadvantages of SiPMs so that it can be generally utilized as an upgrade from a PMT. A simple cooling component and recently developed optical crosstalk suppression method are adopted to reduce the noise which is more serious for larger-area SiPMs. A dedicated readout circuit increases the response frequency and reduces the number of readout channels. We favorably compare this design with a conventional PMT and obtain both higher photon detection efficiency and larger-area acceptance.

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Dynamic range extension of SiPM detectors with the time-gated operation

Cited by 8 publications

References 14 publications

Fluorescence Multi-Detection Device Using a Lensless Matrix Addressable microLED Array

Fluorescence Multi-Detection Device Using a Lensless Matrix Addressable microLED Array

Quantum characteristics and applications of multi‐pixel photon counter

High-sensitivity low-noise photodetector using large-area silicon photomultiplier

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