2023
DOI: 10.3390/ijms24087476
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Dynamic Regulation of Lipid Droplet Biogenesis in Plant Cells and Proteins Involved in the Process

Abstract: Lipid droplets (LDs) are ubiquitous, dynamic organelles found in almost all organisms, including animals, protists, plants and prokaryotes. The cell biology of LDs, especially biogenesis, has attracted increasing attention in recent decades because of their important role in cellular lipid metabolism and other newly identified processes. Emerging evidence suggests that LD biogenesis is a highly coordinated and stepwise process in animals and yeasts, occurring at specific sites of the endoplasmic reticulum (ER)… Show more

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Cited by 4 publications
(3 citation statements)
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“…WT profiles during seed imbibition. AtSEIPIN encodes an endoplasmic reticulum membrane protein exclusive to developing embryos that is involved in the biogenesis of LD (Zhao et al, 2023). AtCLO1 is expressed exclusively during seed development and has also been implicated in LD degradation (Naested et al 2000;Kim et al, 2011).…”
Section: Transcriptomic Analysis and Reserve Mobilisation In Atg7 Mut...mentioning
confidence: 99%
“…WT profiles during seed imbibition. AtSEIPIN encodes an endoplasmic reticulum membrane protein exclusive to developing embryos that is involved in the biogenesis of LD (Zhao et al, 2023). AtCLO1 is expressed exclusively during seed development and has also been implicated in LD degradation (Naested et al 2000;Kim et al, 2011).…”
Section: Transcriptomic Analysis and Reserve Mobilisation In Atg7 Mut...mentioning
confidence: 99%
“…Hepatocytes accumulate lipids as droplets in MAFLD [19]. The lipid droplets (LDs) sequester the excessive supply of FFAs as triglycerides (TGs) [20,21]. In addition, FFAs can be metabolized by β-oxidation in mitochondria [22].…”
Section: Introductionmentioning
confidence: 99%
“…In addition, FFAs can be metabolized by β-oxidation in mitochondria [22]. LDs are highly dynamic organelles that can vary in number and size and that store TGs and other lipids [20,21]. However, excessive lipid droplet formation is detrimental [23].…”
Section: Introductionmentioning
confidence: 99%