Dynamic skin behaviors in cephalopods

Shook, Erica N.; Barlow, George Thomas; Garcia-Rosales, Daniella; Gibbons, Connor J.; Montague, Tessa G.

doi:10.1016/j.conb.2024.102876

Cited by 3 publications

(1 citation statement)

References 102 publications

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“…This loss of the shell has made octopuses acquire characteristics that differentiate them from other molluscs and that allows them a life much more evolved life to thrive in the environment in which they live. Such is the case with their movements of propulsion, their camouflage through special cells (chromatophores) or their high vision capacity, the efficiency of the movement of their arms, their highly developed nervous system with learning capacity, or the presence of a wide neuronal network with a very complex brain and a centralized nervous system (Hochner, 2008;Gutnick et al, 2020;Shook et al, 2024). The presence of all these highly evolved features concerning other species of the same phylum made it in an excellent model species for multiple physiological and neurological biomedical studies (Di Cosmo et al, 2018), as well as for behavioral research (Grant et al, 2006;Hochner, 2008).…”

Section: Introductionmentioning

confidence: 99%

Cryopreservation Enables Long-Term Studies ofOctopus vulgarisHemocyte Immune Functions

Costa,

Paredes,

Peleteiro

et al. 2024

Preprint

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As with their nervous system and other physiological traits, the immune system of cephalopods, in general, and of the common octopus, Octopus vulgaris, in particular, could also present highly evolved characteristics compared to other classes of molluscs. However, to date, there is not much information about it, and studying the defense mechanisms is a key step in understanding their response system to external aggressions and, thus, having the tools to anticipate animal health problems and ensure their welfare. The lack of cell cultures in molluscs is a major problem when carrying out in vitro assays that help to deepen the knowledge of the main immune cells of this species. Cryopreservation becomes an alternative to maintain viable and functional cells after freezing/thawing processes, allowing a larger repertoire of studies to be performed with the same sample or to perform time courses. Having access to good quality cells for long periods will allow to cover a larger repertoire of studies with the same sample or to perform time courses, avoiding logistic bottlenecks that could arise due to the loss of viability and/or functionality of the cells on the lab bench, the lack of time to develop all the desired assays in the same day or the possible losses derived from transporting the samples between different laboratories. Additionally, high-quality suspensions of viable and functional cells are required for successful massive sequencing studies, such as single-cell analysis, where these aspects are the key to an optimal identification. We show here the first functional results from cryopreserved octopus hemocytes, where the cells were able to maintain viability above 80% after two months post cryopreservation and storage at -80C and their functional ability to phagocytose bacteria similar to fresh cells. Our data revealed that the acclimation process after thawing was essential to recovering the functional activity of the cells. The results presented here will facilitate the study of the functions of the most important immune cells of this species and will provide tools for cell preservation in other molluscs species.

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Section: Introductionmentioning

confidence: 99%

Cryopreservation Enables Long-Term Studies ofOctopus vulgarisHemocyte Immune Functions

Costa,

Paredes,

Peleteiro

et al. 2024

Preprint

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Cephalopod-Inspired Nanomaterials for Optical and Thermal Regulation: Mechanisms, Applications and Perspectives

Zhang,

Wang,

Xie

et al. 2024

ACS Nano

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The manipulation of interactions between light and matter plays a crucial role in the evolution of organisms and a better life for humans. As a result of natural selection, precise light-regulatory systems of biology have been engineered that provide many powerful and promising bioinspired strategies. As the "king of disguise", cephalopods, which can perfectly control the propagation of light and thus achieve excellent surroundingmatching via their delicate skin structure, have made themselves an exciting source of inspiration for developing optical and thermal regulation nanomaterials. This review presents cuttingedge advancements in cephalopod-inspired optical and thermal regulation nanomaterials, highlighting the key milestones and breakthroughs achieved thus far. We begin with the underlying mechanisms of the adaptive color-changing ability of cephalopods, as well as their special hierarchical skin structure. Then, different types of bioinspired nanomaterials and devices are comprehensively summarized. Furthermore, some advanced and emerging applications of these nanomaterials and devices, including camouflage, thermal management, pixelation, medical health, sensing and wireless communication, are addressed. Finally, some remaining but significant challenges and potential directions for future work are discussed. We anticipate that this comprehensive review will promote the further development of cephalopod-inspired nanomaterials for optical and thermal regulation and trigger ideas for bioinspired design of nanomaterials in multidisciplinary applications.

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The RNA Revolution in the Central Molecular Biology Dogma Evolution

Haseltine,

Patarca

2024

IJMS

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Human genome projects in the 1990s identified about 20,000 protein-coding sequences. We are now in the RNA revolution, propelled by the realization that genes determine phenotype beyond the foundational central molecular biology dogma, stating that inherited linear pieces of DNA are transcribed to RNAs and translated into proteins. Crucially, over 95% of the genome, initially considered junk DNA between protein-coding genes, encodes essential, functionally diverse non-protein-coding RNAs, raising the gene count by at least one order of magnitude. Most inherited phenotype-determining changes in DNA are in regulatory areas that control RNA and regulatory sequences. RNAs can directly or indirectly determine phenotypes by regulating protein and RNA function, transferring information within and between organisms, and generating DNA. RNAs also exhibit high structural, functional, and biomolecular interaction plasticity and are modified via editing, methylation, glycosylation, and other mechanisms, which bestow them with diverse intra- and extracellular functions without altering the underlying DNA. RNA is, therefore, currently considered the primary determinant of cellular to populational functional diversity, disease-linked and biomolecular structural variations, and cell function regulation. As demonstrated by RNA-based coronavirus vaccines’ success, RNA technology is transforming medicine, agriculture, and industry, as did the advent of recombinant DNA technology in the 1980s.

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Dynamic skin behaviors in cephalopods

Cited by 3 publications

References 102 publications

Cryopreservation Enables Long-Term Studies ofOctopus vulgarisHemocyte Immune Functions

Cryopreservation Enables Long-Term Studies ofOctopus vulgarisHemocyte Immune Functions

Cephalopod-Inspired Nanomaterials for Optical and Thermal Regulation: Mechanisms, Applications and Perspectives

The RNA Revolution in the Central Molecular Biology Dogma Evolution

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