Dynamic telecytopathology of on site rapid cytology diagnoses for pancreatic carcinoma

Kim, Burton; Chhieng, David C.; Crowe, David R.; Jhala, Darshana; Jhala, Nirag; Winokur, Thomas S.; Eloubeidi, Mohamad A.; Eltoum, Isam

doi:10.1186/1742-6413-3-27

Cited by 54 publications

(57 citation statements)

References 26 publications

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“…They did not evaluate procedure time. Kim et al [7] focused on pancreatic carcinoma and described an average total of 12 min required for telecytology, of which an average of 7.5 min were actually devoted to diagnosis because of the approximately 2 min required for whole slide scanning. They retrospectively identified 40 pancreatic cases and used only a select number of slides to review per case.…”

Section: Discussionmentioning

confidence: 99%

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Implementation of Telecytology for Immediate Assessment of Endoscopic Ultrasound-Guided Fine-Needle Aspirations Compared to Conventional On-Site Evaluation: Analysis of 240 Consecutive Cases

Marotti

Johncox

et al. 2012

Acta Cytologica

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Objective: To evaluate the implementation of telecytology in an academic cytology service for immediate assessment of endoscopic ultrasound (EUS) and endobronchoscopic ultrasound (EBUS) fine-needle aspiration (FNA). Study Design: Telecytology was evaluated over a 10-month period. Using an Olympus BX41® microscope and an Olympus DP72® camera with Olympus cellSens® software, real-time dynamic images of air-dried Diff-Quik®-stained smears were transmitted by a cytopathology fellow or cytotechnologist using a secure internet connection. The cytopathologists remotely accessed the real-time images on a computer in their office and rendered immediate assessments. Mean procedure times, and preliminary and final diagnoses were compared between telecytology and conventional on-site evaluation. Results: Two hundred and forty consecutive EUS-FNA and EBUS-FNA procedures with immediate assessments were performed during the evaluation period, of which 158 (66%) utilized telecytology and 82 (34%) did not utilize telecytology. The mean procedure time required for cytotechnologists and cytology fellows was 1.1 h for both conventional on-site and telecytology evaluations. The mean procedure time for cytopathologists was 0.74 h for conventional on-site evaluations and 0.2 h for telecytology. Conclusions: Incorporation of telecytology for immediate assessment of EUS-FNA increased cytopathologist efficiency.

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Section: Discussionmentioning

confidence: 99%

“…A few recent studies have shown comparable accuracy and adequacy for telecytology when compared to conventional on-site evaluation [5,6,7,8]. One of our department’s quality incentives for 2010 was to improve cytopathologist efficiency by reducing cytopathologist procedure time by at least 50%.…”

Section: Introductionmentioning

confidence: 99%

Implementation of Telecytology for Immediate Assessment of Endoscopic Ultrasound-Guided Fine-Needle Aspirations Compared to Conventional On-Site Evaluation: Analysis of 240 Consecutive Cases

Marotti

Johncox

et al. 2012

Acta Cytologica

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“…In the present study we show that, in our setting, TeleCyP can provide a very rapid assessment both with EBUS (average 53.2 s) in the training phase and with EUS in the validation (average 49.2 s) phase of the study. A prior study also utilized a retrospective assessment to determine the time needed by dynamic telecytology as a modality for providing RFI for specimen adequacy [23]. Authors analyzed 40 EUS-FNA samples of the pancreas on preselected retrospective slides.…”

Section: Discussionmentioning

confidence: 99%

TeleCyP (Telecytopathology): Real-Time Fine-Needle Aspiration Interpretation

2012

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Objective: To assess the application of TeleCyP for real-time fine-needle aspiration interpretation (RFI) necessary for case management and specimen triage. Study Design: Twenty-two endobronchial ultrasound (EBUS)-guided mediastinal and pulmonary cases were included in the learning phase to determine the time and efficiency of TeleCyP. Slides were scanned by a cytopathology fellow in real time, and high-speed transmitted images over a secure network were interpreted by a cytopathologist while maintaining audio communication. In the validation phase, an additional 38 pancreas cases from endoscopic ultrasound (EUS) were evaluated recapitulating the RFI scenario from the learning phase. The cytopathologist was blinded to the results of the diagnosis in both phases. Results: The time to provide assessment of specimen adequacy and a preliminary diagnosis was 53 s in the learning phase and 49 s in the validation phase. There was 100% correlation between RFI and TeleCyP assessment for specimen adequacy. TeleCyP particularly posed challenges in providing definitive interpretation on EUS-fine-needle aspiration of some of the pancreatic solid masses (11%, 4/36). Conclusion: TeleCyP can serve as a powerful alternative, time-efficient strategy to provide RFI, and for specimen triaging which is critical for personalized medicine and patient management.

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“…[1011121314151617181920232425] Dynamic systems appear to be more accurate compared with static systems. [678]…”

Section: Discussionmentioning

confidence: 99%

Rapid on-site evaluation with dynamic telecytopathology for ultrasound-guided fine-needle aspiration of head and neck nonthyroid lesions

Khurana

Wang

et al. 2015

Journal of Pathology Informatics

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Background:Rapid on-site evaluation (ROSE) at the time of ultrasound-guided fine-needle aspiration (USGFNA) of head and neck lesion is essential for obtaining adequate samples and providing the preliminary diagnosis. We summarize our experience with ROSE of USGFNA on head and neck nonthyroid lesions using telecytopathology.Materials and Methods:Real-time images of Diff-Quik stained cytology smears were obtained at ultrasound suite with an Olympus DP-70 digital camera attached to an Olympus CX41 microscope, and transmitted via ethernet by a cytotechnologist to a cytopathologist in cytopathology laboratory who rendered a preliminary diagnosis. Live communication was conducted with Vocera voice communication system. The ultrasound suite was located on different floor from the cytopathology laboratory. Accuracy of ROSE via telecytopathology was compared with an equal number of cases that received ROSE, prior to introduction of telecytopathology, via conventional microscopy.Results:Rapid on-site evaluation was performed on a total of 116 USGFNA of head and neck nonthyroid lesions. The telecytopathology system and conventional microscopy was used to evaluate equal number of cases (58 each). Preliminary diagnoses of benign, atypical/suspicious for malignancy, and positive for malignancy were 72.4%, 17.2% and 10.3% for telecytopathology, and 69.0%, 10.3% and 20.7% for conventional microscopy. None of the cases were deemed unsatisfactory. The overall concordance between the preliminary and final diagnoses was 94.8% for telecytopathology and 98.3% for conventional microscopy and was not statistically significant (P = 0.309). The causes of discordant preliminary and final diagnoses were mainly attributed to availability of cell block and Papanicolaou-stained slides for review or flow cytometry results for lymphoma cases at the time of final sign out.Conclusions:Telecytopathology is comparable with conventional microscopy in ROSE of USGFNA of head and neck nonthyroid lesions.

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Dynamic telecytopathology of on site rapid cytology diagnoses for pancreatic carcinoma

Cited by 54 publications

References 26 publications

Implementation of Telecytology for Immediate Assessment of Endoscopic Ultrasound-Guided Fine-Needle Aspirations Compared to Conventional On-Site Evaluation: Analysis of 240 Consecutive Cases

Implementation of Telecytology for Immediate Assessment of Endoscopic Ultrasound-Guided Fine-Needle Aspirations Compared to Conventional On-Site Evaluation: Analysis of 240 Consecutive Cases

TeleCyP (Telecytopathology): Real-Time Fine-Needle Aspiration Interpretation

Rapid on-site evaluation with dynamic telecytopathology for ultrasound-guided fine-needle aspiration of head and neck nonthyroid lesions

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