The status and some recent developments in computational modeling of flexible multibody systems are summarized. Discussion focuses on a number of aspects of flexible multibody dynamics including: modeling of the flexible components, constraint modeling, solution techniques, control strategies, coupled problems, design, and experimental studies. The characteristics of the three types of reference frames used in modeling flexible multibody systems, namely, floating frame, corotational frame, and inertial frame, are compared. Future directions of research are identified. These include new applications such as micro- and nano-mechanical systems; techniques and strategies for increasing the fidelity and computational efficiency of the models; and tools that can improve the design process of flexible multibody systems. This review article cites 877 references.