1999
DOI: 10.1002/(sici)1097-0282(19990415)49:5<355::aid-bip2>3.0.co;2-x
|View full text |Cite
|
Sign up to set email alerts
|

Dynamic twisting correlations in a model DNA with uniform torsion elastic constant

Abstract: The extent to which the twisting motions of two separate subunits (base pairs) in an elastic filament are correlated is discussed in terms of the two‐point correlation function of their azimuthal angular displacements C(Δ,t) ≡ 〈(ϕm(t) − ϕm(0))(ϕn(t) − ϕn(0))〉, where m,n are the sequential subunit indices and Δ = |m − n| is their absolute difference. An approximate expression is derived for C(Δ,t) for an infinitely long model DNA from the analytical theory developed previously to treat the decay of the fluoresc… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
6
0

Year Published

2000
2000
2015
2015

Publication Types

Select...
4
1

Relationship

2
3

Authors

Journals

citations
Cited by 5 publications
(6 citation statements)
references
References 28 publications
0
6
0
Order By: Relevance
“…This uniformity could be inferred from the close similarity of the best-fit α values obtained by fitting the FPA data over different time-spans (0–18, 0–35, 0–70, and 0–120 ns). , The FPA measurement is sensitive to dynamic twisting correlations between the probe dye and its surrounding base pairs. Such correlations extend over increasingly greater distances from the probe with increasing time span of the experiment up to ∼200 bp’s at 120 ns . The absence of such variations in α with time span argues that the ethidium probe was sampling domains of such large size, that it was rarely within 200 bp’s of a boundary between domains of significantly different torsional rigidity.…”
Section: Discussionmentioning
confidence: 96%
See 1 more Smart Citation
“…This uniformity could be inferred from the close similarity of the best-fit α values obtained by fitting the FPA data over different time-spans (0–18, 0–35, 0–70, and 0–120 ns). , The FPA measurement is sensitive to dynamic twisting correlations between the probe dye and its surrounding base pairs. Such correlations extend over increasingly greater distances from the probe with increasing time span of the experiment up to ∼200 bp’s at 120 ns . The absence of such variations in α with time span argues that the ethidium probe was sampling domains of such large size, that it was rarely within 200 bp’s of a boundary between domains of significantly different torsional rigidity.…”
Section: Discussionmentioning
confidence: 96%
“…Such correlations extend over increasingly greater distances from the probe with increasing time span of the experiment up to ∼200 bp's at 120 ns. 39 The absence of such variations in α with time span argues that the ethidium probe was sampling domains of such large size, that it was rarely within 200 bp's of a boundary between domains of significantly different torsional rigidity. Such large domains are the hallmark of a highly cooperative structural transition.…”
Section: ■ Discussionmentioning
confidence: 99%
“…Each HM shows a strong covariance of coordinate displacements along the sequence. Under the assumption that distortions in the modes relax with different characteristic relaxation times (due to different characteristic diffusion constants), correlated motions may extend much farther along the sequence (Schurr and Fujimoto, 1999).…”
Section: Discussionmentioning
confidence: 99%
“…The internal dynamics in DNA has been studied extensively using a variety of spectroscopic techniques such as nuclear magnetic resonance (NMR), electron spin resonance (ESR), ,, fluorescence polarization anisotropy (FPA), and depolarized dynamic light scattering (DDLS), , as well as the new method of time-resolved Stokes shifts (TRSS) …”
Section: Introductionmentioning
confidence: 99%