2023
DOI: 10.3390/fractalfract7030258
|View full text |Cite
|
Sign up to set email alerts
|

Dynamical Analysis of Generalized Tumor Model with Caputo Fractional-Order Derivative

Abstract: In this study, we perform a dynamical analysis of a generalized tumor model using the Caputo fractional-order derivative. Tumor growth models are widely used in biomedical research to understand the dynamics of tumor development and to evaluate potential treatments. The Caputo fractional-order derivative is a mathematical tool that is recently being applied to model biological systems, including tumor growth. We present a detailed mathematical analysis of the generalized tumor model with the Caputo fractional-… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
13
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
9

Relationship

1
8

Authors

Journals

citations
Cited by 49 publications
(13 citation statements)
references
References 42 publications
0
13
0
Order By: Relevance
“…Fractional calculus enables the differentiation and integration of non-integer orders, extending beyond traditional calculus. Cancer research finds application by modeling anomalous diffusion processes, characterizing tumor behavior more accurately, and incorporating memory effects into models, deepening our understanding of tumor dynamics [59][60][61][62].…”
Section: Mathematical Modelingmentioning
confidence: 99%
“…Fractional calculus enables the differentiation and integration of non-integer orders, extending beyond traditional calculus. Cancer research finds application by modeling anomalous diffusion processes, characterizing tumor behavior more accurately, and incorporating memory effects into models, deepening our understanding of tumor dynamics [59][60][61][62].…”
Section: Mathematical Modelingmentioning
confidence: 99%
“…Let's verify the condition 2. By replacing λ in the characteristic equation (6) by 'iω' we separate the real and imaginary parts and equation (11) is obtained; then by solving (11)-(b), the Hopf bifurcation frequency ω = ω Hopf that provides the frequency of stable oscillations is then given by equation (12) meanwhile equation (13) defines the critical value βc of β that corresponds to the Hopf bifurcation point for the system.…”
Section: Hopf Bifurcationmentioning
confidence: 99%
“…To predict these different phenomena in a given system, several analysis tools for dynamic systems are needed, including : Time series, which allow the trajectory of the system to be observed over time; phase portraits, which characterise the presence of an attractor; bifurcation diagrams, which indicate the values taken asymptotically by a system as a function of its control parameter; the Lyapunov exponent, which provides information on the degree of sensitivity of the system to its initial conditions; and basins of attraction, which provide information on the set of initial conditions for which the trajectories of the system converge towards one of its attractors. In the biological and medical fields, the usefulness of this approach is well established; for example, we can mention the dynamic study of the growth of tumour cells (carcinogenic or not) [12,13], the dynamic study of renal function subjected to the consumption of water highly concentrated with magnesium and calcium particles [14], the study of a model of influenza disease [15], the study of a minimal glucose-insulin model [16], as well as the study of heartbeat models based on coupled nonlinear oscillators which has gained increasing interest since the work of Gois et al [17]; They formulated the heartbeat model as a system of three coupled non-autonomous modified Van der Pol oscillators [18] as this allowed on one hand to reproduce the electrocardiogram(ECG) signal of a healthy heart and on the other hand that of a diseased heart for some pathological behaviours (i.e. fibrillation, tachycardia, bradycardia) under certain conditions.…”
Section: Introductionmentioning
confidence: 99%
“…Furthermore, a study of COVID-19 dynamics in Thailand has been carried out [ 27 ]. Furthermore, a thorough investigation has been carried out on the application of the Caputo fractional-order derivative in the dynamical analysis of a generalized tumor model [ 28 ]. Finally, a study has been conducted [ 29 ] on dual-wave solutions for the Kadomtsev-Petviashvili model that include second-order temporal and spatial-temporal dispersion factors.…”
Section: Introductionmentioning
confidence: 99%