2017
DOI: 10.1039/c6ra25200a
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Dynamics of different steps of the photopyrolytic cycle of an eminent anticancer drug topotecan inside biocompatible lyotropic liquid crystalline systems

Abstract: In the present work, we have explored the dynamics of different steps of photopyrolytic processes of an eminent anticancer drug topotecan (TPT) inside the biocompatible reverse hexagonal (H II ), gyroid (Ia3d) cubic and diamond (Pn3m) cubic lyotropic liquid crystalline (LLC) phases. Both steady state and timeresolved area normalized emission spectrum (TRANES) demonstrate the generation of an excited state zwitterionic (Z*) form of TPT in all LLC phases attributed to an excited state intermolecular proton trans… Show more

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References 68 publications
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