Dynamics of Morphometric Bone Changes in the Site of Mandibular Perforation Defect in Rats With Toxic Hepatitis and Use of Hepatoprotector

Annotation. The purpose of the study is to investigate the features of the local manifestation and clinical course of lichen planus in the oral cavity. The relevance of the mentioned problem is due to the growing share of patients with lichen planus, the undefined etiology and pathogenesis of this disease, the lack of a single point of view on treatment tactics and the search for opportunities for more effective treatment. 21 patients who were diagnosed with lichen planus with manifestation on the mucous membrane of the oral cavity were examined. The age of the patients ranged from 28 to 57 years. The studied patients were divided into 2 groups: the first – the main one (12 patients), which received a standard treatment scheme; the second – control (9 patients) included patients who received an etiopathogenetic treatment scheme with the inclusion of appropriate drugs. All patients underwent clinical examinations of the manifestation of the local status in the form of an assessment of pain, hyperemia, swelling, in points as follows: 1 point – no sign, 2 – slightly expressed, 3 – expressed, 4 - significantly expressed. As a result of observing the manifestations of the primary impression elements in the oral cavity, the following results were obtained. In the group of patients who received standard treatment, the healing of the primary elements of the impression of lichen planus had significantly less positive dynamics, in contrast to the group of patients who received the proposed treatment scheme. All local manifestations of the impression elements on the mucous membrane of the tongue, cheeks, and lips, which were taken into account during the examination, showed a significantly positive effect of the proposed treatment on the local signs of healing of the impression elements of the oral mucosa in lichen planus red (p<0.05). Analyzing the obtained indicators of the clinical manifestation of pain, hyperemia, swelling of the mucous membrane of the oral cavity of the patients, their positive dynamics and synchronicity are noticeable in patients of both groups. In case of lichen planus of the mucous membrane of the oral cavity, local clinical manifestations have significantly positive dynamics when using the proposed etiopathogenetic scheme of treatment (p<0.05). It was revealed that the treatment of lichen planus should be complex and etiopathogenetic, which should combine general and local treatment. The proposed etiopathogenetic scheme of treatment will reduce the recovery time of patients with lichen planus of the oral cavity by 4-5 days and improve the social adaptation of patients.

Section: список посилань -Referencesmentioning

confidence: 99%

Clinical manifestations of elements of oral mucosa infection in patients with lichen ruber planus

Polishchuk,

Shinkaruk-Dykovytska

2023

Study of the stability of dental implants on the background of the hepatobiliary system pathology

Polishchuk

2023

Annotation. Today, dental implantation is one of the most important methods for restoring dental defects. This method allows restoration of tooth row defects without preparation of hard tooth tissues. Endoosseous dental implantation in patients with concomitant pathology requires special attention, among which pathology of the hepatobiliary system stands out, which has recently tended to increase. This is primarily due to the epidemiology of viral hepatitis, deterioration of the external environment, and complex social conditions of life. The purpose of our work was to investigate the stability of dental implants using the analysis of frequency-resonance indicators in patients with hepatobiliary system pathology. A study of the stability coefficient was conducted in 26 patients who had intraosseous dental implants installed. All patients were divided into 2 groups: the first – main (14 patients) – without pathology of the hepatobiliary system; the second – comparative (12 patients) - included patients who had disorders of the hepatobiliary system, which were established on the basis of the collected anamnesis and violations of biochemical indicators. There were equal numbers of men and women in each group. There were 8 (57.2%) women and 6 (42.8%) men in the first group, and 5 (41.7%) men and 7 (58.3%) women in the second group. For all patients, dental intraosseous implantation was performed in one or two zones of included defects. After the installation of dental intraosseous implants, the stability of the dental implant was determined using a frequency-resonance study. Similar studies were also conducted after the opening of the dental implants before the installation of the orthopedic structure after 6 months. The results. We found a significant difference in the coefficient of stability of dental implants in patients with hepatobiliary system pathology and without liver pathology (p<0.05). In the main research group, the following coefficients of stability of dental implants were obtained: immediately after the installation of dental implants intraoperatively, a study of indicators was carried out, which corresponded to the level of 70,41±2,97 points, and already after 6 months this indicator of the stability coefficient in±creased and was fixed at the level 75,41±2,59 points. In the patients of the second research group (comparison), immediately after the installation of dental implants, the stability coefficient was at the level of 42.56±3.53 points, and 6 months after the installation of dental implants – 44,39±3,26 points. Liver pathology negatively affects the coefficient of stability of dental implants and their osseointegration, worsening them by 1,7 times. With liver pathology, osteopenia is observed, which requires preoperative and postoperative hepatoprotective correction and osteotropic therapy.

Clinical course of wound healing in patients with odontogenic phlegmons of the maxillofacial area with concomitant liver pathology

Polishchuk,

Dalishchuk

2024

Annotation. The purpose of the work is to study the features of the clinical course of healing of postoperative purulent wounds in patients with odontogenic phlegmons of the maxillofacial area on the background of concomitant chronic liver pathology. The relevance of this problem is due to the growing share of patients with odontogenic inflammatory processes of the maxillofacial area, as well as with chronic liver pathology. It is known that liver diseases have a negative effect on periodontal tissue diseases, that again complicates their course. However, information on the peculiarities of the course of purulent wounds in odontogenic phlegmons on the background of concomitant liver pathology is insufficient and requires in-depth study and observation, since the inability of the liver to fully perform its antimicrobial function leads to the development of a dysbiotic syndrome in the oral cavity, which will be manifested by bacteremia, endotoxinemia and thereby worsen the clinical course of the inflammatory process. Based on the results of a scientific and theoretical analysis of literature sources, the state of research related to the study of the healing indicators of oral cavity tissues in periodontal diseases, facial injuries, dental implantation is highlighted. At the same time, it was found that there are not enough studies devoted to the treatment of odontogenic phlegmons of the maxillofacial area, which requires further development and implementation in practice using more effective treatment and prevention measures.