Dynamics of terminal fraying–peeling and hydrogen bonds dictates the sequential <i>vs</i>. cooperative melting pathways of nanoscale DNA and PNA triplexes

Mandal, Sandip; Ganesh, Krishna N.; Maiti, Prabal K.

doi:10.1039/d4nr01104j

Nanoscale

2024

DOI: 10.1039/d4nr01104j

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Dynamics of terminal fraying–peeling and hydrogen bonds dictates the sequential vs. cooperative melting pathways of nanoscale DNA and PNA triplexes

Sandip Mandal,

Krishna N. Ganesh,

Prabal K. Maiti

Abstract: Two-step melting of DNA–DNA–DNA triplex vs. one-step cooperative melting of PNA–DNA–PNA triplex.

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Supramolecular polyplexes from Janus peptide nucleic acids (bm-PNA-G5): self-assembled bm-PNA G-quadruplex and its tetraduplex with DNA

Todkari,

Chaudhary,

Kulkarni

et al. 2024

Org. Biomol. Chem.

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Supramolecular polyplexes from Janus peptide nucleic acids (bm-PNA-G5): self-assembled bm-PNA G-quadruplex and its tetraduplex with DNA

Todkari,

Chaudhary,

Kulkarni

et al. 2024

Org. Biomol. Chem.

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show abstract

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Dynamics of terminal fraying–peeling and hydrogen bonds dictates the sequential vs. cooperative melting pathways of nanoscale DNA and PNA triplexes

Abstract: Two-step melting of DNA–DNA–DNA triplex vs. one-step cooperative melting of PNA–DNA–PNA triplex.

Cited by 1 publication

References 84 publications

Supramolecular polyplexes from Janus peptide nucleic acids (bm-PNA-G5): self-assembled bm-PNA G-quadruplex and its tetraduplex with DNA

Supramolecular polyplexes from Janus peptide nucleic acids (bm-PNA-G5): self-assembled bm-PNA G-quadruplex and its tetraduplex with DNA

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