The work provides information on the emergency care for post-traumatic stress disorders complicated by psychosis. Emphasis is placed on cases of severe depression with suicidal manifestations and alcoholic complications with disorders of consciousness and psychosis. It is noted that in recent years, typical cases of post-traumatic stress disorder have often become more complicated and aggravated, because the debilitating nature of mental trauma persists in modern life due to military events. Therefore, in the clinical picture of psychogenic disorders, severe depressive states with suicidal tendencies can develop. In such cases, moodiness dominates, as well as episodes of significant melancholy that a patient experiences as torment, physical suffering. Ideas of self-accusation arise, which are closely related to the psychotraumatic situation and constitute the dominant content of a psychogenic complex. Patients blame themselves of the emerging trouble. Under the influence of such experiences, exacerbations develop with an increase in anxiety, hopelessness, suicidal thoughts with intentions and actions; sleep and appetite deteriorate, retardation, apathy, and indifference develop. Such conditions are more likely to occur in conditions of family trouble, in persons with weak personal psychological protection in a decreased tolerance to emotional stress, altered self-esteem. In other cases, patients with post-traumatic stress disorders become withdrawn, alienated, and spiteful. People can experience difficulties when communicating with others, they become irritable, sometimes aggressive. At this time, patients refuse to fulfill the traditional requirements of professional activity. In families, they become strangers, estranged from their relatives. Therefore, over time, they may lose their jobs and families. Characteristics of psychopathic behavior can predispose individuals to alcoholism and drug addiction, which in turn contribute significantly to social and micro-social maladaptation. When providing urgent care to such patients, it is necessary to be guided by the requirements of the legislation on psychiatric care. In the acute period, antidepressant, neuroleptic and sedative therapy in injections should be prescribed to quickly achieve the desired therapeutic effect, followed by switching to oral forms of basic and adjuvant therapy. Psychocorrectional measures should also be an important component of the process of further rehabilitation of patients with post-traumatic stress disorder.