This paper reports on the study of vibration acceleration in milling and vibration prediction by means of artificial neural networks. The milling process, carried out on AZ91D magnesium alloy with a PCD milling cutter, was monitored to observe the extent to which the change of selected technological parameters (vc, fz, ap) affects vibration acceleration ax, ay and az. The experimental data have shown a significant impact of technological parameters on maximum and RMS vibration acceleration. The simulation works employed the artificial neural networks modelled with Statistica Neural Network software. Two types of neural networks were employed: MLP (Multi-Layered Perceptron) and RBF (Radial Basis Function).