Dynapenic abdominal obesity as predictor of mortality and disability worsening in older adults: A 10-year prospective study

Rossi, Andrea P.; Fantin, Francesco; Caliari, Cesare; Zoico, Elena; Mazzali, Gloria; Zanardo, Marina; Bertassello, Paolo; Zanandrea, Valeria; Micciolo, Rocco; Zamboni, Mauro

doi:10.1016/j.clnu.2015.02.005

Cited by 65 publications

(85 citation statements)

References 29 publications

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“…Authors suggest that a standardized definition of sarcopenic obesity is required, because the vast majority of included studies consider only one of the measurements for sarcopenia classification, according to recent consensus: MS or muscle mass, and none of them considered muscle function. In this sense, we believe that if MS is considered a proxy to sarcopenia, the better terminology should be dynapenic obesity, as already referred to in other publications …”

Section: Discussionmentioning

confidence: 79%

“…Despite these limitations, this study presented several positive outcomes. Measurement of WC and the handheld dynamometer are easy to use and widely available instruments capable of identifying people with a higher risk of developing physical impairments and mortality . In addition, path analysis allowed us to evaluate complex associations that interact, which is an advantage over traditional regression analysis .…”

Section: Discussionmentioning

confidence: 99%

“…Body composition changes with aging are well studied in the literature: fat deposit in the abdominal region or intramuscular, and reduction of lean mass . Progressive loss of skeletal mass related to poorer muscle function or strength characterizes a geriatric syndrome called sarcopenia …”

Section: Introductionmentioning

confidence: 99%

“…An interest in studying sarcopenia/dynapenia and obesity has been growing recently, as can be seen by the increasing number of publications on this theme and the recent published meta‐analysis . It has been proposed that sarcopenic obesity in older adults could have a synergic effect on each other, and would be associated with worse functional disability, higher cardiovascular and metabolic syndrome risks …”

Section: Introductionmentioning

confidence: 99%

“…However, results regarding older adults’ mortality and the presence of sarcopenic/dynapenic obesity are not always homogeneous, probably because many risk factors should be considered, such as the presence of chronic diseases (CD), that plays an important role in inflammatory response, oxidative stress and metabolic pathways …”

Section: Introductionmentioning

confidence: 99%

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Association of dynapenia, obesity and chronic diseases with all‐cause mortality of community‐dwelling older adults: A path analysis

Komatsu

Borim

Néri

et al. 2018

Geriatrics Gerontology Int

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Aim The objective of the present study was to evaluate the effect of dynapenia, central obesity and the presence of chronic diseases in 8‐year mortality of community‐dwelling older adults. Methods Participants comprised 610 older adults, aged ≥65 years at baseline, who participated in the “Frailty in Brazilian Older People” study carried out in 2008. Baseline data, such as weight, height, waist circumference, muscle strength, sex, self‐reported diseases and physical activity, were assessed. Vital status in 2016 was assessed by Mortality Information System database of Campinas. The χ2‐test and Mann–Whitney U‐test were used to compare categorical and continuous variables, respectively. Path analysis was carried out to study the factors associated with mortality. Results There was a statistical difference between alive and deceased groups for the variables sex, age group, physical activity, waist circumference and dynapenia. Path analysis explored the relationship among the studied variables. Direct paths showed a positive association to mortality for those who presented the combination of more diseases (β = 0.105), male sex (β = 0.108), low physical activity (β = 0.121), low handgrip strength (β = 0.090) and no central obesity (β = −0.143). When indirect paths were concerned, variables “central obesity”, the presence of “more diseases” and dynapenia had a mediator role. Conclusions Central obesity was not positively associated with higher mortality, unless it was associated with the presence of chronic diseases. Dynapenia showed a direct effect on mortality, but not combined with central obesity. The findings of this study shed light on complex relationships between nutritional status and elderly mortality through the use of simple measurements. Geriatr Gerontol Int 2019; 19: 108–112.

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Section: Discussionmentioning

confidence: 79%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Association of dynapenia, obesity and chronic diseases with all‐cause mortality of community‐dwelling older adults: A path analysis

Komatsu

Borim

Néri

et al. 2018

Geriatrics Gerontology Int

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Sarcopenic Obesity

et al. 2021

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Sex and body composition influences the Quilombolas strength

Pereira

Santana

Lamarca

et al. 2020

JCSM Clinical Reports

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BackgroundStudies in ethnic minority communities with social isolation have low genetic variability. Furthermore, assuming that any attempt to determine ageing by chronological cuts is misleading, it is recommended that functional capacity assessments be performed especially during and at the end of adulthood. Specifically, muscle strength performance is an interesting screening measure of functional capacity because of its association with functional level. However, the behaviour of the muscle strength manifestation between sexes and its association with body composition (BC) parameters in a low genetic variability community are unknown. Therefore, the objective of this study was to verify the influence of BC and sex on the handgrip strength of mature remaining Quilombolas.MethodsSeventy Quilombola volunteers of both sexes (♀ = 39; ♂ = 31) were recruited. BC and muscle strength were tested by dual‐energy X‐ray absorptiometry (DEXA) and handgrip equipment (Jamar), respectively. Correlations between muscle strength and age and BC parameters were determined by Spearman equation. In addition, it has executed comparisons of BC and age between strongest and weakest men and women from the interquartile analysis by Mann–Whitney U test. The significance level was adopted: P ≤ 0.05.ResultsOf the 70 remaining Quilombolas, with a mean age 64.6 ± 7.07 years, 55.7% were women with a mean age of 63.77 ± 7.56 years and 44.3% men with 65.65 ± 7.87 years. Statistical differences were identified for all parameters of BC and performance evaluated between men and women, except for the ratio of appendicular and axial fat‐free mass (P = 0.183). The evaluation of the influence of BC on strength identified that Quilombola men and women have different processes in the decline of strength, considering both the correlation's tests and the comparisons between groups of different degrees of strength.ConclusionsFor Quilombola individuals, strength is a variable that can be modulated due to the influence of gender and BC.

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Dynapenic abdominal obesity as predictor of mortality and disability worsening in older adults: A 10-year prospective study

Cited by 65 publications

References 29 publications

Association of dynapenia, obesity and chronic diseases with all‐cause mortality of community‐dwelling older adults: A path analysis

Association of dynapenia, obesity and chronic diseases with all‐cause mortality of community‐dwelling older adults: A path analysis

Sarcopenic Obesity

Sex and body composition influences the Quilombolas strength

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