Dysautonomia and dysphagia

Sparberg, Marshall; Knudsen, Kermit B.; Frank, Saunders T.

doi:10.1212/wnl.18.5.504

Cited by 15 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These findings are comparable to other studies obtained in patients with autonomic neuropathy due to diabetes mellitus 14 and strongly suggest abnormal visceral autonomic nervous function in patients with achalasia. This view of a generalized disorder of the autonomic nervous system in achalasia of the oesophagus is also supported by reports indicating achalasia‐like oesophageal manifestations in various classical autonomic disorders 29 –33…”

Section: Discussionsupporting

confidence: 59%

Autonomic dysfunction in patients with achalasia of the oesophagus

Herbay

Heyer

Olk

et al. 1998

Neurogastroenterology Motil

View full text Add to dashboard Cite

It has been suggested that achalasia is associated with extraoesophageal sympathetic and parasympathetic dysfunction. In a prospective study we applied conventional ultrasonography and duplex sonography to investigate basal and postprandial peak systolic velocity (PSV), pulsatility index (PI) and resistance index (RI) of superior mesenteric artery and PSV of portal vein in nine patients with achalasia and 10 healthy controls (study I). In addition, in eight of these patients autonomic nervous function was investigated by pupillary function tests as well as cardiovascular reflex tests and compared with eight age- and sex-matched controls (study II). The results indicated that postprandial increase of PSV in the superior mesenteric artery was significantly lower, and postprandial decrease of PI and RI significantly higher in achalasia compared to healthy controls. In contrast, postprandial increase of PSV in the portal vein was not significantly different between both groups. Autonomic function tests revealed significant lower maximal pupillary contraction and redilatation velocities, significantly lower heart rate variation during orthostasis, deep respiration test and Valsalva manoeuvre in achalasia compared to controls. It is concluded that achalasia is associated with extraoesophageal autonomic nervous dysfunction that involves cardiovascular and pupillary function as well as regulation of mesenteric arterial blood flow.

show abstract

Section: Discussionsupporting

confidence: 59%

Autonomic dysfunction in patients with achalasia of the oesophagus

Herbay

Heyer

Olk

et al. 1998

Neurogastroenterology Motil

View full text Add to dashboard Cite

show abstract

“…Among them, the frequen cy of the gene appears to be about 1% [Rotem, 1970]. The affection has never theless been observed fairly often in other races [Riley et al, 1954;Linde, 1955;Grossman et al, 1956;Filer, 1957;Stadler, 1958;Braun-Vallon and Bessman, 1960;Mould, 1962;Joseph and Job, 1963;Russell and Avery, 1963;Burke, 1966;Sparberg et al, 1968;Ginsberg et al, 1972, personal observation].…”

Section: Hereditymentioning

confidence: 99%

The Riley-Day Syndrome

Francois¹

1977

Ophthalmologica

View full text Add to dashboard Cite

“…A large number of congenital and acquired neural, muscular, and neuromuscular diseases interfere with normal swallowing [1][2][3][4]. Well-documented congenital or genetic diseases associated with abnormal deglutition during childhood include: Mobius syndrome, Friedreich's ataxia, familial dysautonomia, and cerebral palsy [5][6][7][8][9][10].…”

mentioning

confidence: 99%

Derangement of swallowing in children with myelomeningocele

Fernbach

McLone

1985

Pediatr Radiol

View full text Add to dashboard Cite

Barium esophagrams performed in 13 children with myelomeningocele demonstrated a variety of swallowing disorders: difficulty in bolus formation, nasopharyngeal reflux, tracheobronchial aspiration. Cricopharyngeal spasm was not identified in this group. Antegrade peristalsis in the distal two-thirds of the esophagus was normal. Gastroesophageal reflux was demonstrated in 8 of the children. Vocal cord paralysis (8/13) and death in early children (7/13) occurred with greater frequency than in the general myelomeningocele population. Correct management of these children may require tracheostomy, gastrostomy, and fundoplication.

show abstract

Dysautonomia and dysphagia

Cited by 15 publications

References 0 publications

Autonomic dysfunction in patients with achalasia of the oesophagus

Autonomic dysfunction in patients with achalasia of the oesophagus

The Riley-Day Syndrome

Derangement of swallowing in children with myelomeningocele

Contact Info

Product

Resources

About