Dysfunctional Adipocytes in Cardiovascular Biology239PDE5 inhibition ameliorates visceral adiposity targeting the miR-22 / SIRT1 pathway: evidence from the CECSID trial237AMP-activated protein kinase activation partially restores the anti-contractile effect of perivascular adipose tissue in male offspring of obese dams238Peroxisome proliferator activated receptor (PPAR)alpha-gamma agonist aleglitazar attenuates tumor necrosis factor(TNF)alpha-mediated inflammation and insulin resistance in human adipocytes