Dysfunctional Eating Patterns and Symptoms of Pica in Children and Adolescents with Sickle Cell Disease

Lemanek, Kathleen L.; Brown, Ronald T.; Armstrong, F. Daniel; Hood, Catherine; Pegelow, Charles H.; Woods, Gerald M.

doi:10.1177/000992280204100706

Cited by 21 publications

(11 citation statements)

References 28 publications

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“…Ivascu et al 2 published a retrospective review of 480 patients with SCD that reported a pica prevalence ranging from 14.8% to 23.3% in the age group of 10–19 years. Lemanek et al 3 have reported a significant association between disease severity (increased frequency of care‐giver and child reported pain episodes) with care‐giver ratings of dysfunctional eating patterns. Dysfunctional eating patterns may represent a coping mechanism to the stress associated with chronic and recurrent pain.…”

Section: Discussionmentioning

confidence: 99%

Sickle cell disease and plumbism in children

Issaivanan

Ahmed

Shekher

et al. 2009

Pediatric Blood & Cancer

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Childhood lead poisoning is common, affects multiple organs and is preventable. Co-existence of plumbism and sickle cell disease (SCD) is uncommon, with major overlap in signs and symptoms. We describe a patient with SCD and plumbism. Dysfunctional eating patterns may cause ingestion and increased absorption of lead in these patients. Routine screening for pica and other dysfunctional eating habits with appropriate behavioral interventions is emphasized. Annual screening for lead in patients with SCD of all ages (1-21years) and supplementation of micronutrients like zinc and iron in deficient cases may help prevent plumbism in these patients.

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Section: Discussionmentioning

confidence: 99%

Sickle cell disease and plumbism in children

Issaivanan

Ahmed

Shekher

et al. 2009

Pediatric Blood & Cancer

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“…8 BEZOAR Children with SCD have an increased incidence of pica, the mouthing or eating of nonfood items. 9 The incidence of pica decreases with age, but it is as high as 50% in preschoolaged children with SCD. 9 Although rare, gastric or intestinal bezoars resulting from ingestion of hair or foam can be lifethreatening.…”

Section: Hepatic Sequestrationmentioning

confidence: 99%

“…9 The incidence of pica decreases with age, but it is as high as 50% in preschoolaged children with SCD. 9 Although rare, gastric or intestinal bezoars resulting from ingestion of hair or foam can be lifethreatening. [10][11][12] While taking the history of a child with SCD and abdominal pain, one must remember to ask about eating nonfood items.…”

Section: Hepatic Sequestrationmentioning

confidence: 99%

Abdominal Pain in Children With Sickle Cell Disease

Rhodes

Bates

Andrews

et al. 2014

Journal of Clinical Gastroenterology

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The differential diagnosis of abdominal pain is broad in any child, and further complicated in children with sickle cell disease (SCD). Acute causes of abdominal pain may require emergent surgery, such as for appendicitis or obstruction caused by a bezoar. Rapid intervention is necessary and life-saving in children with SCD and acute splenic or hepatic sequestration. The majority of children with SCD presenting to the physician's office or emergency department will have subacute reasons for their abdominal pain, including but not limited to constipation, urinary tract infection, peptic ulcer disease, and cholecystitis. Vaso-occlusive pain often presents in children as abdominal pain, but is a diagnosis of exclusion. The case of a 10-year-old girl with intermittent abdominal pain is used as a starting point to review the pathophysiology, diagnosis, and treatment of the most acute and common causes of abdominal pain in children with SCD.

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“…Although one fourth of SCD children are affected by pica, it has not gained the focus of health care providers. Searching for biological explanations makes the clinician focus on aspects unrelated to psychological stressors [ 67 ].…”

Section: Introductionmentioning

confidence: 99%

Precipitating factors and targeted therapies in combating the perils of sickle cell disease--- A special nutritional consideration

et al. 2016

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Nutritional research in sickle cell disease has been the focus in recent times owing to not only specific nutritional deficiencies, but also the improvements associated with less painful episodes. Though hydroxyurea remains the drug of choice, certain adverse health effects on long term supplementation makes room for researches of different compounds. Macro and micro nutrient deficiencies, along with vitamins, play an important role in not only meeting the calorific needs, but also reducing clinical complications and growth abnormalities. Symptoms of hyper protein metabolism, increased cell turnover, increased cardiac output, and appetite suppression due to enhanced cytokine production, might give us leads for better understanding of the mechanisms involved. Different nutritional approaches comprising of traditional herbal therapies, antioxidants, flavonoids, vitamins, minerals etc., reducing oxidative stress and blood aggregation, have been tried out to increase the health potential. Nutritional therapies may also serve complementary to the newer therapies using ozone, hematopoietic stem cell transplantation, antifungal medications, erythropoietin etc. Herein we try to present a holistic picture of the different patho-physiological mechanisms, and nutritional strategies adopted.

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Dysfunctional Eating Patterns and Symptoms of Pica in Children and Adolescents with Sickle Cell Disease

Cited by 21 publications

References 28 publications

Sickle cell disease and plumbism in children

Sickle cell disease and plumbism in children

Abdominal Pain in Children With Sickle Cell Disease

Precipitating factors and targeted therapies in combating the perils of sickle cell disease--- A special nutritional consideration

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