Dysfunctional Uterine Bleeding

Mazur, Michael T.; Kurman, Robert J.

doi:10.1007/978-0-387-26321-2_5

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…Thirty‐eight specimens showing secretory‐type endometria with asynchronous glands (25 hysterectomy and 13 biopsy specimens) were retained for study (Table 1). Asynchronous glands were defined as glands displaying cellular features >4 days apart in the endometrial cycle 8 . Patients’ ages ranged from 35 to 53 years (mean 45 ± 8).…”

Section: Summary Of 38 Cases In the Studymentioning

confidence: 99%

Histopathogenesis of endometrium with asynchronous glands in dysfunctional uterine bleeding

et al. 2009

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diagnosis. Of particular interest in our case was the presence of parasitized cells, randomly scattered in the centrofollicular areas. The cells were confirmed as macrophages rather than follicular dendritic cells by positivity for CD68 and negativity for CD23 and CD35 on immunohistochemistry. To our knowledge, this surprising finding has not been previously reported.We report this case to highlight the existence of this unusual clinicopathological presentation of leishmaniasis in an immunocompetent patient. Leishmanial lymphadenitis must be systematically considered when confronted with any adenopathy of unknown origin in endemic areas.

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Section: Summary Of 38 Cases In the Studymentioning

confidence: 99%

Histopathogenesis of endometrium with asynchronous glands in dysfunctional uterine bleeding

et al. 2009

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Endometrial intravascular thrombi are typically associated with shedding but may be the sentinel feature of an underlying thrombotic disorder

Stewart

2020

Histopathology

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AimsFollowing the identification of endometrial intravascular thrombi (IVT) as the presenting feature in a patient with antiphospholipid syndrome, additional biopsy specimens were reviewed to determine the frequency and histological associations of IVT in the endometrium.Methods and ResultsEighty‐five additional biopsies were reviewed including 44 consecutive cases demonstrating shedding changes (both menstrual and non‐cyclical), 30 cases without shedding (normal and non‐cyclical), and 11 cases in which unusually prominent IVT had been recorded upon initial histological assessment. In the shedding group, IVT were significantly more common in biopsies showing disordered proliferative endometrium (DPE, 4/7 cases) than normal menstrual appearances (4/22 cases), and organising vascular changes were seen only in the former. IVT in DPE cases were also commonly multifocal and sometimes involved abnormal ectatic vessels. None of the 30 non‐shedding cases demonstrated IVT. Eight of the 11 biopsies with prominent IVT demonstrated DPE and shedding but three cases demonstrated otherwise normal cyclical appearances.ConclusionsIVT may be seen occasionally in normal menstrual endometrium but are more characteristic of DPE, and organising vascular changes are suggestive of abnormal haemostasis. An underlying thrombotic disorder may be considered when endometrial IVT occur in the absence of shedding changes.

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The role of syndecan-1 during endometrial carcinoma progression

Solmaz

2019

J Can Res Ther

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Dysfunctional Uterine Bleeding

Cited by 3 publications

References 19 publications

Histopathogenesis of endometrium with asynchronous glands in dysfunctional uterine bleeding

Histopathogenesis of endometrium with asynchronous glands in dysfunctional uterine bleeding

Endometrial intravascular thrombi are typically associated with shedding but may be the sentinel feature of an underlying thrombotic disorder

The role of syndecan-1 during endometrial carcinoma progression

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