Dysglycaemia and 90 day and 1 year risks of death or readmission in patients hospitalised for community-acquired pneumonia

Eurich, Dean T.; Gamble, John‐Michael; Marrie, Thomas J.; Majumdar, Sumit R.

doi:10.1007/s00125-009-1598-y

Cited by 21 publications

(14 citation statements)

References 22 publications

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“…[1][2][3][4] Most previous research in this area has focused on the relationship between dysglycaemia and specific conditions 2-4 on admission to specialist care facilities (eg different intensive care units). 5 In this study, we investigate the relationship between dysglycaemia and length of hospital stay, shortterm (28-day) mortality and readmissions in an unselected acute medical unit (AMU) population.…”

Section: Introductionmentioning

confidence: 99%

Assessing the relationship between admission glucose levels, subsequent length of hospital stay, readmission and mortality

Evans

Dhatariya

2012

Clinical Medicine

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-This study aimed to investigate relationships between dysglycaemia and length of hospital stay, short-term mortality and readmission in an unselected population in an acute medical unit (AMU). The rate of follow up in non-diabetic individuals with hyperglycaemia was also measured. We analysed data from all 1,502 patients admitted through our AMU in February 2010 to assess blood glucose levels on admission, length of stay, 28-day readmissions and mortality, and to determine whether blood glucose у у11.1 mmol/l on admission in non-diabetic individuals was followed up. In total, blood glucose was measured on admission for 893 patients. Mean length of stay was 8.8 (standard deviation 11.9) days, for patients with blood glucose Ͻ Ͻ6.5 mmol/l on admission; 11.3 (13.6) days, for 6.5-7 mmol/l; 10.2 (14.5) days, for 7.1-9 mmol/l; 10.6 (14.9) days, for 9.1-11mmol/l; 12 (18.4) days, for 11.1-20 mmol/l and 9.1 (11.2) days, for Ͼ Ͼ20.1 mmol/l. Length of stay for patients with blood glucose Ͼ Ͼ6.5 mmol/l on admission was significantly longer (pϭ ϭ0.002). The 28-day readmission rates were 6.4%, 6%, 9.7%, 12.5%, 10% and 15%, respectively, and 28-day death rates were 4.8%, 6%, 5.8%, 17.2%, 17.1% and 6.1%, respectively. Overall, 51.4% of non-diabetic individuals with blood glucose Ͼ Ͼ11.1 mmol/l on admission were followed up. The study showed that blood glucose Ͼ Ͼ6.5 mmol/l on admission is associated with significantly longer length of stay. Hyperglycaemia was associated with increased 28-day mortality and readmissions, and is frequently underinvestigated.

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Section: Introductionmentioning

confidence: 99%

Assessing the relationship between admission glucose levels, subsequent length of hospital stay, readmission and mortality

Evans

Dhatariya

2012

Clinical Medicine

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“…Diabetes was associated with prolonged LOS and LOIVAB, but only LOS remained significant after adjusting for confounders. Hyperglycaemia has been associated with excess mortality in patients admitted to ICUs [17] and in CAP patients with hyperglycaemia [9, 10, 18], although the literature is inconsistent [13, 14]. In 2012, L epper et al [10] found, in a large prospective multicentre cohort study of CAP, that hyperglycaemia is strongly associated with 90 day mortality in patients without DM.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have suggested that hyperglycaemia may be associated with severe outcome in a range of conditions, including sepsis [1, 7, 8]. In some CAP studies, an association with higher mortality has also been reported [9–12], while others have shown no association [13, 14]. Most studies have focused on the association between hyperglycaemia and long-term mortality (28–90 day mortality) after an episode of CAP [10, 13].…”

Section: Introductionmentioning

confidence: 99%

“…In some CAP studies, an association with higher mortality has also been reported [9–12], while others have shown no association [13, 14]. Most studies have focused on the association between hyperglycaemia and long-term mortality (28–90 day mortality) after an episode of CAP [10, 13]. Thus, there is a need for further analysis on the impact of hyperglycaemia on morbidity and mortality associated with CAP, and particularly in-hospital mortality.…”

Section: Introductionmentioning

confidence: 99%

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The impact of blood glucose on community-acquired pneumonia: a retrospective cohort study

et al. 2017

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Hyperglycaemia is common in patients with community-acquired pneumonia (CAP) and is a predictor of severe outcomes. Data are scarce regarding whether this association is affected by diabetes mellitus (DM) and also regarding its importance for severe outcomes in hospital. We determined the impact of blood glucose on severe outcomes of CAP in hospital.We studied 1318 adult CAP patients hospitalised at three Danish hospitals. The association between blood glucose and DM status and severe clinical outcome (admission to an intensive care unit (ICU) and/or in-hospital mortality) was assessed by logistic regression. Models were adjusted for CURB-65 score and comorbidities.12% of patients had DM. In patients without DM an increase in admission blood glucose was associated with risk for ICU admittance (OR 1.25, 95% CI 1.13–1.39), but not significantly associated with in-hospital mortality (OR 1.10, 95% CI 0.99–1.23). In patients with DM an increase in admission blood glucose was not associated with ICU admittance (OR 1.05, 95% CI 1.00–1.12) or in-hospital mortality (OR 1.05, 95% CI 0.99–1.12).An increase in admission blood glucose (only in patients without DM) was associated with a higher risk for ICU admittance and a trend towards higher in-hospital mortality. DM was not associated with a more severe outcome of CAP.

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“…Sowohl Hypo-als auch Hyperglykämien sind während stationärer Aufenthalte mit längerer Aufenthaltsdauer, schlechtem Outcome bis hin zum Tod in Verbindung zu bringen [1][2][3]. Daher zielen die meisten Leitlinien auf eine sichere Blutzuckereinstellung unter Vermeidung von Hypo-und Hyperglykämien ab.…”

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GlucoTab – Diabetesmanagement im Krankenhaus

Aberer

Mader

2019

J. Klin. Endokrinol. Stoffw.

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Dysglycaemia and 90 day and 1 year risks of death or readmission in patients hospitalised for community-acquired pneumonia

Abstract: Aims/hypothesis The aim of this study was to investigate whether dysglycaemia at admission is associated with adverse events at 90 days or 1 year in a population

Cited by 21 publications

References 22 publications

Assessing the relationship between admission glucose levels, subsequent length of hospital stay, readmission and mortality

Assessing the relationship between admission glucose levels, subsequent length of hospital stay, readmission and mortality

The impact of blood glucose on community-acquired pneumonia: a retrospective cohort study

GlucoTab – Diabetesmanagement im Krankenhaus

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