Dyslipidaemia in a Black African diabetic population: burden, pattern and predictors

Abstract

ObjectivesThis study sought to assess the burden, pattern and predictors of dyslipidaemia in 425 adult diabetic patients in Uganda.ResultsThe median (IQR) age of the study participants was 53 (43.5–62) years with a female majority (283, 66.9%). Dyslipidaemia defined as presence of ≥ 1 lipid abnormalities was observed in 374 (88%) study participants. Collectively, the predictors of dyslipidaemia were: female gender, study site (private hospitals), type of diabetes (type 2 diabetes mellitus), statin therapy, increased body mass index and diastolic blood pressure. Proactive screening of dyslipidaemia and its optimal management using lipid lowering therapy should be emphasised among adult diabetic patients in Uganda.Electronic supplementary materialThe online version of this article (10.1186/s13104-017-2916-y) contains supplementary material, which is available to authorized users.

Prevalence of dyslipidemia and associated risk factors among adult residents of Mekelle City, Northern Ethiopia

“…This is consistent with the findings documented elsewhere [11,21,[46][47][48][49][50][51][52]. However, studies conducted in China [53] and Thailand [33] reported contradictory findings. The possible explanation for this result might be, as age increases the level of activity and intensity of work decreases, which leads to excessive fat accumulation.…”

“…The prevalence of elevated triglyceride (40.2%) in this study is higher than the previous findings reported in Senegal (7.1%) [37], Nigeria (9.9%) [38], Ethiopia (21.0%) [30], and Malawi (28.7%) [39]. However, it is consistent with the study findings reported in Venezuela (39.7%) [40], Jordan (41.9%) [36], and Uganda (42.1%) [33]. But lower than the findings documented in Thailand (49.9%) [32], India (56.1%) [28], South Africa (59.3%) [19], and Brazil (65.3%) [41].…”

“…It is almost similar to study findings reported in India (47.8%) [26] and Iran (50.0%) [31]. But lower than the findings reported in Thailand (56.5%) [32], Uganda (60.9%) [33], Ghana (61.0%) [34], Senegal (66.3%) [35], and Jordan (75.9%) [36]. These differences might be attributed to the variations in the cutoffs, level of urbanization, study settings, lifestyle, and socioeconomic status.…”

“…However, it is lower than the previous study reported in Ethiopia (33.7%) [11]. On the other hand, the prevalence of total cholesterol in this study is higher than the study findings reported in different African countries [9,30,[33][34][35]37]. The prevalence of low HDL-C (16.5%) in the present study is almost similar to the previous studies done in different African countries including Malawi (15.9%) [39], Ghana (17.0%) [34], and…”

Bio-Electric Impedance Analysis and Anthropometric Obesity Indices as Predictors of Dyslipidaemia Among Adults at A Tertiary Institution in Lusaka, Zambia.

“…The ndings were similar to those in a large population survey in the United States among the Caucasians (36), the Tehranian men (37) and among the Mediterranean population (38) but in contrast with other studies, including a meta-analysis, which favoured WHtR as the best predictor of dyslipidaemia (28,30,32). Additionally, our study ndings also contradicted some African studies that have favoured BMI as the best predictor for dyslipidaemia such as studies among the Sudanese and Ugandans which indicated BMI to be a strong predictor of dyslipidaemia (39,40). However, these studies did not utilise the methods looking at body fat distribution.…”