Dyslipidaemia prevalence and associated risk factors in the United Arab Emirates: a population-based study

Abstract

ObjectivesTo determine and describe the prevalence and pattern of dyslipidaemia and its associated risk factors among an adult Emirati population.DesignPopulation-based, cross-sectional study.SettingAdults living in the Northern Emirates.Participants824 adult participants (51.8% men, 48.2% women, mean age 42.8±13.4 years old).Primary outcome measuresFasting blood samples were collected, blood pressure and waist circumference were measured.ResultsThe overall dyslipidaemia prevalence was 72.5%, with 42.8% of the participants showing high total cholesterol (TC) level, 29% showing high triglyceride (TG) level, 42.5% showing low high-density lipoprotein cholesterol (HDL-C) level, 38.6% showing high low-density lipoprotein cholesterol (LDL-C) level and 72.3% showing high cholesterol ratio. The regression models showed that gender was a significant predictor of a high TG level, low LDL-C level and high cholesterol ratio. Middle-aged individuals (30–59 years old) had a significantly higher risk of having high TC, TG and LDL-C levels than young (<30 years old) and elderly (≥60 years old) individuals. Diabetes mellitus was a significant predictor of low TC, high TG and low HDL-C levels, while central obesity was a significant predictor of a high TG level, low HDL-C level and high cholesterol ratio. Smoking was a significant predictor of a high TG level only in men.ConclusionsThe prevalence of dyslipidaemia was considerably high among the local adult Emiratis. The identified dyslipidaemia predictors were gender, age, smoking, central obesity and diabetes. Further studies are recommended to assess other important risk factors and aggressive preventive measures in the United Arab Emirates.

Dyslipidemia and Associated Risk Factors in the Elderly Population in Asmara, Eritrea: Results from a Community-Based Cross-Sectional Study

“…For instance, research suggests that vigorously contracting muscle can release large quantities of myokines with auto-, para-, and endocrine effects. The best-studied myokine is Interleukin-6 (IL-6) which, among a myriad of functions, stimulates β -cell proliferation, reduces stress induced β -cell apoptosis, and increases glucose transporter (GLUT4) translocation, thus, basal glucose uptake [ 36 ]. Moreover, the well-documented benefits of physical activity supersede molecular adaptations of working skeletal muscle and include improvement of coronary endothelial function, enhancement of muscle strength and power, and reduction in the aging process or sarcopenia.…”

“…Interestingly, a strong association between WC (a surrogate marker of visceral adiposity), FPG, elevated DBP, and multiple dyslipidemias persisted in the multivariable logistic regression analysis. These associations have been observed in younger cohorts [25,36]. From a more practical perspective, computed tomography (CT) studies have demonstrated that visceral adiposity is more closely related to lipid, glucose, and blood pressure abnormalities [37].…”

Dyslipidemias and 10-Years Cardiovascular Risk Scores in Adults in Asmara, Eritrea: Findings From a Community-Based Cross-Sectional Study

“…However, comparable results have been reported by some investigators in the region. A study conducted in Nigeria reported a frequency of 85.9% 6 , 67.3% in South Africa 19 , United Arab Emirates 72.5% 21 , Makelle city, Northern Ethiopia (66.7%) 22 , India (ICMR-INDIAB study) (79%) 23 , Northern China (31.2%) 24 , and USA (52%) 25 . Separately, some estimates of the prevalence of dyslipidemia among adults in Africa place the value between 15% to about 50% 4,26 .…”

Value of the Clinical Pharmacist Interventions in the Application of the American College of Cardiology (ACC/AHA) 2018 Guideline for Cholesterol Management

“…In the United Arab Emirates (UAE), ischemic heart diseases and stroke are among the top 3 leading causes of years of life lost (YLL) and mortality according to a global burden disease study in 2016 (3). Another recent study in UAE showed that the overall prevalence of dyslipidemia among adults was 72.5%, where the total cholesterol and LDL-C levels were high in 42.8% and 38.6% of the participants, respectively (4). In addition, a study including an expatriate population in the UAE reported a high prevalence of either overweight or obesity (75.3%) as well as known associated risk factors for developing both metabolic syndrome and dyslipidemia (5).…”