Dyslipidemia and its associated factors among adult diabetes outpatients in West Shewa zone public hospitals, Ethiopia

Abdissa, Daba; Hirpa, Delessa

doi:10.1186/s12872-022-02489-w

Cited by 18 publications

(15 citation statements)

References 29 publications

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“…Poor glycaemic control is strongly associated with the development of diabetic foot over time ( 50 ). Although the prevalence of unbalanced diabetes was only 36.4% in the present study, previous studies by Fawzy et al ( 48 ) and Abdissa and Hirpa ( 41 ), show a much higher frequency among patients with diabetic feet, at 89 and 63.8%, respectively. These same studies showed that high levels of HbA1c can contribute to the development of the diabetic foot.…”

Section: Discussioncontrasting

confidence: 74%

“…Sex, advancing age, long duration of diabetes, increased body-mass index (BMI) and high blood pressure were risk factors associated with the prevalence of dyslipidaemia ( 39 ). In addition, dyslipidaemia has been previously considered to be an independent predictor of the development of cardiovascular diseases ( 40 , 41 ). In the present study, a close association between obesity (translated into high BMI) and diabetic foot was found, which was consistent with findings from specialized studies ( 42 , 43 ).…”

Section: Discussionmentioning

confidence: 99%

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Risk assessment of amputation in patients with diabetic foot

Tănăsescu

Sabău²,

Moisin³

et al. 2022

Exp Ther Med

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The prevalence of diabetes has increased dramatically over the past decade, especially in developing countries, reaching pandemic proportions. Although has been the most important factor influencing the prevalence of type 2 diabetes, the prevalence of type 2 diabetes is on the increase among younger adults. The subsequent rate of increase with age is variable, which is more evident in societies where the general prevalence of the disease is higher. Based on clinical and statistical data obtained from the patients who were admitted to The First and Second Surgery Wards in the Sibiu County Emergency University Clinical Hospital (Sibiu, Romania) and the Proctoven Clinic (Sibiu, Romania) between January 2018 and December 2020, the present study attempted to devise a risk score that can be applied for the benefit of patients. The ultimate aim was that this risk score may be eventually applied by diabetologists and surgeons to assess the risk of amputation in patients with diabetic foot lesions. An important part in the therapeutic management of diabetic foot injuries is the assessment of risk factors. Using this risk score system devised, the risk factors that were found to exert influence in aggravating diabetic foot injuries are smoking, obesity, dyslipidaemia, unbalanced diabetes mellitus (glycated haemoglobin ≥7.5%), duration of diabetes >5 years, hepatic steatosis and the co-existence of various heart diseases. To conclude, all these risk factors aforementioned can decrease the effectiveness of treatment and can have a significant impact on the quality of life, if they are not well known.

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Section: Discussioncontrasting

confidence: 74%

Section: Discussionmentioning

confidence: 99%

Risk assessment of amputation in patients with diabetic foot

Tănăsescu

Sabău²,

Moisin³

et al. 2022

Exp Ther Med

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show abstract

“…In a systematic review of 177 studies at African sites, the prevalence of elevated total cholesterol concentrations, low HDL cholesterol concentrations, and elevated triglyceride concentrations were 34.4%, 39.5% and 3.9%, respectively [19]. A recent study at public hospitals in Ethiopia among mostly urban T2D participants reported dyslipidemia prevalence of 81.5%, with elevated TG being the most common lipid abnormality [20]. A study in South Africa among T2D participants showed dyslipidemia rates of 94.0% and 84.0% among males and females, respectively [21].…”

Section: Introductionmentioning

confidence: 99%

Dyslipidemia in Adults with Type 2 Diabetes in a Rural Community in Ganadougou, Mali: A Cross-Sectional Study

Diawara¹,

Coulibaly²,

Koné³

et al. 2023

Preprint

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Dyslipidemia is a disorder where abnormally lipid concentrations circulate in the bloodstream. The disorder is common in type 2 diabetics (T2D) and is linked with T2D comorbidities, particularly cardiovascular disease. Dyslipidemia in T2D is typically characterized by elevated plasma triglyceride and low high-density lipoprotein cholesterol (HDL-C) levels. There is a significant gap in the literature regarding dyslipidemia in rural parts of Africa, where lipid profiles may not be routinely captured through standard surveillance activities. This study aimed to characterize the prevalence and demographic profile of dyslipidemia in T2D patients in the rural community of Ganadougou, Mali. We performed a cross-sectional study of 104 subjects with T2D in Ganadougou between November 2021 and March 2022. Demographic and lipid profiles were collected through cross-sectional surveys and blood tests. The overall prevalence of dyslipidemia in T2D patients was 87.5% (91/104), which did not differ by sex (p = .368). High low-density lipoprotein cholesterol (LDL-C) was the most common lipid abnormality (78.9%, [82/104]). Dyslipidemia was associated with age and hypertension status (p = .013 and p = .036, respectively). High total and high LDL-C parameters were significantly associated with hypertension (p = .029 and p = .006, respectively). In low-resource settings such as rural Mali, there is a critical need to improve infrastructure for routine dyslipidemia screening to guide its prevention and intervention approaches. The high rates of dyslipidemia observed in Gandadougou, consistent with concomitant increases in cardiovascular diseases in Africa suggest that lipid profile assessments should be incorporated into routine medical care for T2D patients in African rural settings.

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“…In a systematic review of 177 studies at African sites, the prevalence of elevated total cholesterol concentrations, low HDL cholesterol concentrations, and elevated triglyceride concentrations were 34.4%, 39.5% and 3.9%, respectively [20]. A recent study at public hospitals in Ethiopia among mostly urban T2D participants reported dyslipidemia prevalence of 81.5%, with elevated TG being the most common lipid abnormality [21]. A study in South Africa among T2D participants showed dyslipidemia rates of 94.0% and 84.0% among males and females, respectively [22].…”

Section: Introductionmentioning

confidence: 99%

Dyslipidemia in adults with type 2 diabetes in a rural community in Ganadougou, Mali: A cross-sectional study

Diawara

Coulibaly

Fofana

et al. 2023

Preprint

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Dyslipidemia is a disorder where abnormally lipid concentrations circulate in the bloodstream. The disorder is common in type 2 diabetics (T2D) and is linked with T2D comorbidities, particularly cardiovascular disease. Dyslipidemia in T2D is typically characterized by elevated plasma triglyceride and low high-density lipoprotein cholesterol (HDL-C) levels. There is a significant gap in the literature regarding dyslipidemia in rural parts of Africa, where lipid profiles may not be captured through routine surveillance. This study aimed to characterize the prevalence and demo-graphic profile of dyslipidemia in T2D in the rural community of Ganadougou, Mali. We per-formed a cross-sectional study of 104 subjects with T2D in Ganadougou between November 2021 and March 2022. Demographic and lipid profiles were collected through cross-sectional surveys and serological analyses. The overall prevalence of dyslipidemia in T2D patients was 87.5% (91/104), which did not differ by sex (p = .368). High low-density lipoprotein cholesterol (LDL-C) was the most common lipid abnormality (78.9%, [82/104]). Dyslipidemia was associated with age and hypertension status (p = .013 and p = .036, respectively). High total and high LDL-C parameters were significantly associated with hypertension (p = .029 and p = .006, respectively). In low-resource settings such as rural Mali, there is a critical need to improve infrastructure for routine dyslipidemia screening to guide its prevention and intervention approaches. The high rates of dyslipidemia observed in Gandadougou, consistent with concom-itant increases in cardiovascular diseases in Africa suggest that lipid profile assessments should be incorporated into routine medical care for T2D patients in African rural settings.

show abstract

Dyslipidemia and its associated factors among adult diabetes outpatients in West Shewa zone public hospitals, Ethiopia

Cited by 18 publications

References 29 publications

Risk assessment of amputation in patients with diabetic foot

Risk assessment of amputation in patients with diabetic foot

Dyslipidemia in Adults with Type 2 Diabetes in a Rural Community in Ganadougou, Mali: A Cross-Sectional Study

Dyslipidemia in adults with type 2 diabetes in a rural community in Ganadougou, Mali: A cross-sectional study

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