Dyslipidemia Prevalence in Iranian Adult Men: The Impact of Population-Based Screening on the Detection of Undiagnosed Patients

Abstract

PurposeDyslipidemia has been established as one of the most important modifiable risk factors for cardiovascular disease. Due to the higher prevalence of dyslipidemia in males, this study aimed to estimate the prevalence of dyslipidemia in Iranian urban men.Materials and MethodsA screening program was conducted in 845 Iranian men 25 years of age and older in 2014. A health interview survey was conducted to evaluate the prevalence of self-reported dyslipidemia and to collect demographic data, as well as serum lipid profile screening by a reference laboratory. Lipoprotein levels was categorized based on the Adult Treatment Panel III criteria and the data were analyzed using the chi-square test and analysis of variance.ResultsThe overall prevalence of dyslipidemia was 51.8%, and the prevalence of various forms of dyslipidemia was as follows: hypercholesterolemia (≥240 mg/dL), 11.4%; hyper-low-density lipoprotein cholesterol (≥160 mg/dL), 9.6%; hypertriglyceridemia (≥200 mg/dL), 25%; and hypo-high-density lipoprotein (HDL) cholesterol (<40 mg/dL), 34.3%. With the exception of hypo-HDL, all forms of dyslipidemia were significantly less common in men over 65 years of age (p<0.05).ConclusionsThe prevalence of hypo-HDL and hypertriglyceridemia was higher than expected in Iranian adult men, with half of men 25 years of age and older affected by at least one form of dyslipidemia. A large gap in primary and secondary care was observed, because nearly 80% of patients with dyslipidemia were unaware of their status. Urgent preventive programs and lifestyle changes are necessary to reduce the prevalence of cardiovascular risk factors.

Prevalence of combined and noncombined dyslipidemia in an Iranian population

“…Dyslipidemia is a modifiable cardiovascular (CV) risk factor that is manifested as elevated plasma low‐density concentrations of low‐density lipoprotein cholesterol (LDL‐C) or triglycerides (TG), or low plasma high‐density lipoprotein cholesterol (HDL‐C) concentrations . The prevalence of dyslipidemia has an increasing trend in many countries including those located in the Middle East region . The prevalence of both low HDL‐C and high LDL‐C has been reported to be increased in women.…”

“…1 The prevalence of dyslipidemia has an increasing trend in many countries including those located in the Middle East region. 2 The prevalence of both low HDL-C and high LDL-C has been reported to be increased in women. In Iran, the prevalence of hypercholesterolemia is greater in women (38.9% in men and 41.8% in women) but hypertriglyceridemia is more common in men (47% in men and 42.5% in women).…”

The Prevalence and Range of Major Cardiovascular Risk Factors in Iranian Diabetic Adults

“…The sample size of the mentioned study was quite small and inclusion of patients with renal or hepatic diseases and absence of assessing smoking habits were some limitations of that study [20]. Mohammadbeigi et al demonstrated that one out of two men aged at least 25 years affected by at least one form of dyslipidemia [21]. Numerous possible theories have been postulated for explanation of these differences in females vs. males in which one of the most common of them would be different sex hormones, especially estrogen.…”

Association of Body Mass Index with Dyslipidemia among the Government Staff of Kermanshah, Iran: A Cross-Sectional Study

“…In this study, the overall prevalence of hyperlipidemia was reported as 16.6%. Muhammadbeigi et al estimated this prevalence to be 51.8% (18). Similarly, in a meta-analysis study, Tabatabaei et al reported the prevalence of different types of dyslipidemia including hypercholesterolemia, hypertriglyceridemia, and LDL as 41.6%, 46%, and 35%, respectively (19).…”