Dyspeptic Symptoms and Endoscopic Findings in the Community: The Loiano–Monghidoro Study

Zagari, Rocco Maurizio; Law, Graham; Fuccio, Lorenzo; Pozzato, P.; Forman, David; Bazzoli, Franco

doi:10.1038/ajg.2009.706

Cited by 63 publications

(76 citation statements)

References 25 publications

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“…Only 10% of symptomatic patients had typical weekly symptoms; these subjects had a mild form of reflux esophagitis of LA grade A or B. In previous studies, the prevalence of endoscopy-proven reflux esophagitis was 11.8%-27.4%, and 37% of EE had typical symptoms (3,15,(22)(23)(24)(25)(26)(27). In Japan, the prevalence of EE in symptomatic patients was 10.6%-13.8% (15,27) and was 7.1%-7.8% in subjects who had undergone a medical checkup (27,28).…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics and natural history of asymptomatic erosive esophagitis

Jung

Oh²,

Kang³

2014

Turk J Gastroenterol

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Section: Discussionmentioning

confidence: 99%

Clinical characteristics and natural history of asymptomatic erosive esophagitis

Jung

Oh²,

Kang³

2014

Turk J Gastroenterol

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“…Th ese management algorithms were developed on the basis of endoscopic studies of large cohorts of patients with dyspepsia presenting to physicians and also by evaluating patients in the general population who had not sought medical attention for their symptoms. In this issue of the Journal, Zagari et al ( 1 ) report endoscopic fi ndings in a population of subjects from two small Italian villages. Th is and several other studies provide interesting insights into the changing epidemiology of dyspepsia.…”

Section: Introductionmentioning

confidence: 99%

Dyspepsia, Peptic Ulcer, and H. pylori : A Remembrance of Things Past

Vakil

2010

American Journal of Gastroenterology

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Dyspepsia and gastroesophageal refl ux disease are common conditions in clinical practice. Current management strategies emphasize testing and treatment for Helicobacter pylori in the initial management of patients presenting with dyspeptic symptoms in regions where the prevalence of H. pylori infection is > 15 % . Population-based studies in patients with dyspepsia suggest that peptic ulcer disease related to H. pylori infection is decreasing in prevalence, whereas gastroesophageal refl ux disease is becoming a more common cause of dyspeptic symptoms. Unfortunately, symptoms are a poor predictor of endoscopic fi ndings, and alarm features are not a good predictor of an underlying malignancy. Although peptic ulcer disease has declined in Western countries, specifi c populations such as immigrants and rural communities may have a high prevalence of infection and peptic ulcer disease that needs to be considered in initial dyspepsia management, even in areas where the general prevalence of H. pylori infection has declined below 15 % .

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“…1 In Italy it has been estimated to be around 1.5%. 2,3 Chronic gastroesophageal reflux disease (GERD), a spectrum of hiatal hernia, gastroesophageal reflux, heartburn and regurgitation is a risk factor for both BE and erosive esophagitis (E). It is worth noting that GERD is not always present in all patients with endoscopic diagnosis of BE or E and they may also share other modifiable risk factors such as smoking and overweight.…”

Section: Introductionmentioning

confidence: 99%

Association between coffee or tea drinking and Barrett’s esophagus or esophagitis: an Italian study

et al. 2017

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BACKGROUND/OBJECTIVES: Only a few papers have treated of the relationship between Barrett's esophagus (BE) or erosive esophagitis (E) and coffee or tea intake. We evaluated the role of these beverages in BE and E occurrence. SUBJECTS/METHODS: Patients with BE (339), E (462) and controls (619) were recruited. Data on coffee and tea and other individual characteristics were collected using a structured questionnaire. RESULTS: BE risk was higher in former coffee drinkers, irrespective of levels of exposure (cup per day; ⩽ 1: OR = 3.76, 95% CI 1.33-10.6; 41: OR = 3.79, 95% CI 1.31-11.0; test for linear trend (TLT) P = 0.006) and was higher with duration (430 years: OR = 4.18, 95% CI 1.43-12.3; TLT P = 0.004) and for late quitters, respectively (⩽3 years from cessation: OR = 5.95, 95% CI 2.19-16.2; TLT P o 0.001). The risk of BE was also higher in subjects who started drinking coffee later (age 418 years: OR = 6.10, 95% CI 2.15-17.3). No association was found in current drinkers, but for an increased risk of E in light drinkers (o 1 cup per day OR = 1.85, 95% CI 1.00-3.43). A discernible risk reduction of E (about 20%, not significant) and BE (about 30%, P o 0.05) was observed in tea drinkers. CONCLUSIONS: Our data were suggestive of a reduced risk of BE and E with tea intake. An adverse effect of coffee was found among BE patients who had stopped drinking coffee. Coffee or tea intakes could be indicative of other lifestyle habits with protective or adverse impact on esophageal mucosa.

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Dyspeptic Symptoms and Endoscopic Findings in the Community: The Loiano–Monghidoro Study

Cited by 63 publications

References 25 publications

Clinical characteristics and natural history of asymptomatic erosive esophagitis

Clinical characteristics and natural history of asymptomatic erosive esophagitis

Dyspepsia, Peptic Ulcer, and H. pylori : A Remembrance of Things Past

Association between coffee or tea drinking and Barrett’s esophagus or esophagitis: an Italian study

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