Dysphagia in a patient with a history of large B‐cell lymphoma: Esophageal disease with negative biopsy findings

Crook, Terri W.; Robinson, Robert A.

doi:10.1002/dc.10078

Cited by 5 publications

(3 citation statements)

References 17 publications

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“…Radiographic characteristics of esophageal lymphoma have revealed a variety of abnormalities which are similar to lymphoma in other gastrointestinal locations (10). Additionally, Crook and Robinson (23) identified negative biopsy results in a patient with a history of esophageal large B-cell lymphoma, which suggests that analysis of cytological specimens may be required to diagnose lymphoma. According to a previous study which analyzed clinical and pathological results (9), primary esophageal lymphomas typically arise in the lower esophagus.…”

Section: Discussionmentioning

confidence: 99%

Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report

2017

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Primary esophageal natural killer (NK)/T-cell lymphoma is a markedly rare tumor. There were only 6 cases of the disease identified prior to June 2015. In the present study, the aforementioned cases were validated, and relevant computed tomography (CT) results and clinical features of primary esophageal NK/T-cell lymphoma were determined, to increase awareness of this type of tumor. CT features and clinical presentations of a patient with pathologically confirmed esophageal NK/T-cell lymphoma was analyzed. The patient exhibited non-specific clinical symptoms and CT images revealed diffuse thickening of the entire length of the esophagus. The patient received cycles of systemic chemotherapy and subsequent chest CT images demonstrated prompt and marked shrinkage of the tumor. At the time of writing, the patient has survived for 24 months and experiences a good quality of life without postprandial fullness or difficulty swallowing solid food. In addition, the characteristics of 6 patients with complete clinical features of this type of tumor, on the basis of a review of published studies (online PubMed, Medline, Google Scholar, Chinese Biomedicine Database and China Journal Full Text Database search), were retrospectively analyzed. Although primary esophageal NK/T-cell lymphoma is a markedly rare tumor, it is considered to be included in differential diagnosis of patients presenting with a fungal or viral infection, therapy-related mucositis or reflux esophagitis. The final diagnosis of primary esophageal NK/T-cell lymphoma is on the basis of a combination of clinical, CT and histopathological results.

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Section: Discussionmentioning

confidence: 99%

Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report

2017

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“…On CT images, esophageal lymphomas are usually observed as esophageal wall thickening 11,12 or mass formation, 13 although negative findings 14 have also been reported. According to an analysis of endoscopic findings by Kim et al ., 3 esophageal NK/T cell lymphomas have ulcerative or ulceroinfiltrative features.…”

Section: Discussionmentioning

confidence: 99%

Esophageal involvement by extranodal natural killer T cell lymphoma, nasal type, mimicking Ebstein Barr viral esophagitis in a tonsillar lymphoma patient undergoing chemoradiation therapy

Lee

Park

Won

et al. 2010

Asia-Pac J Clncl Oncology

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Esophageal involvement by extranodal natural killer (NK)/T cell lymphoma, nasal type, is rare. As a result, esophageal symptoms in these patients might at first be thought to originate from a benign condition, such as viral esophagitis. It is important to note, however, that benign conditions may mask esophageal involvement by lymphoma. Until now, there has been no report documenting esophageal involvement by lymphoma mimicking viral esophagitis in an extranodal NK/T cell lymphoma patient undergoing active treatment. Here, we report a case of esophageal involvement by extranodal NK/T cell lymphoma, nasal type, initially misdiagnosed as Ebstein Barr virus esophagitis. Lymphoma invasion of the esophagus should be considered if esophageal symptoms do not respond to usual medical esophagitis therapy in an extranodal NK/T cell lymphoma, nasal type, patient undergoing chemoradiation.

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“…In contrast to the pathologic etiology of motility disorders, pseudoachalasia can be caused by infectious or malignant causes. 5,7 High-resolution CT and magnetic resonance imaging may also be useful in distinguishing between the two disorders. Although mechanical obstruction of the distal esophagus by an extrinsic mass is the predominant mechanism by which pseudoachalasia causes its symptoms, studies have been undertaken to suggest that neoplastic infiltration of the esophageal myenteric plexus may also be contributory.…”

Section: Diagnosis In Oncologymentioning

confidence: 99%

Retroperitoneal Diffuse Large B-Cell Lymphoma Presenting As Pseudoachalasia

Pastor

Eggers

Loughran

et al. 2010

JCO

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Dysphagia in a patient with a history of large B‐cell lymphoma: Esophageal disease with negative biopsy findings

Cited by 5 publications

References 17 publications

Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report

Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report

Esophageal involvement by extranodal natural killer T cell lymphoma, nasal type, mimicking Ebstein Barr viral esophagitis in a tonsillar lymphoma patient undergoing chemoradiation therapy

Retroperitoneal Diffuse Large B-Cell Lymphoma Presenting As Pseudoachalasia

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