Dysplastic kidney and not renal agenesis is the commonly associated anomaly in infants with seminal vesicle cyst

Abstract

OBJECTIVE To determine whether the association of seminal vesicle cyst (SVC) and renal anomaly in young children correlates with previously reported cases of SVCs in adolescent and adult patients, as congenital SVCs, although rare, are frequently described in association with ipsilateral renal agenesis, mainly in adolescent and adult patients, whereas reports on SVCs in younger children are sparse. PATIENTS AND METHODS We report on nine infants (median age 4 months) with congenital SVCs, all of them associated with ipsilateral dysplastic kidneys. All patients had ultrasonography of the renal system and voiding cysto‐urethrography. Magnetic resonance imaging was used in two patients. RESULTS The SVCs were found incidentally during ultrasonography for the renal anomaly. Three patients had dysplastic and six had multicystic dysplastic kidneys. In previous reported adult cases of SVCs the most common associated renal anomaly was agenesis of the ipsilateral kidney (25 of 44 cases), whereas only one case of dysplastic kidney was reported. CONCLUSION As the appearance of renal agenesis might result from a former congenital dysplastic kidney, our findings indicate that cases of ipsilateral renal agenesis in adult patients with congenital SVCs might represent former dysplastic or multicystic dysplastic kidney.

Cystic dysplasia of the epididymis: a disorder of mesonephric differentiation associated with renal maldevelopment

“…The most well-characterized examples of excretory duct anomalies associated with renal and/or urinary malformations are congenital absence of the vas deferens (CAVD) and cystic dysplasia of the rete testis (CDRT) [12][13][14][15]; less frequent disorders include seminal vesicle cysts and agenesis, and ectopic deferens/mesonephric duct persistence [4,16,17]. Renal agenesis, usually ipsilateral to the excretory duct malformation, is the commonest type of renal malformation found in these cases; renal dysplasia, hypoplasia, ureteral duplication, and urethral stenosis have also been described.…”

A Case of Cryptorchidism with Ipsilateral Congenital Unilateral Absence of the Vas Deferens and Contralateral Renal Agenesis

“…Congenital unilateral absence of the vas deferens (CUAVD) is an uncommon anomaly, which may contribute to male infertility and it has been associated with renal agenesis and a variety of other anomalies that was first described in 1870 by Reverdin [1]. The anomalies associated with CUAVD include seminal vesicles and ejaculatory ducts anomalies, cryptorchidism, malrotation of the solitary kidney, multicystic kidney, ectopic kidney, and horseshoe kidney and they are often asymptomatic so that they are diagnosed incidentally during orchidopexy or surgical exploration for inguinal hernias or even during evaluation for infertility in adults.…”

Multicystic dysplastic kidney (MCDK) in the neonate: The role of the urologist

“…42,43 Merrot identified ipsilateral malformation of the internal genitalia in 15% of MCDK patients, 12 which has the potential to lead to genitourinary complaints 44 c.…”

“…The known tendency for MCDKs to involute, the low rate of prenatally diagnosed renal agenesis, and the prospective observation of children with MCDK having anomalies of the internal genitalia that persist in spite of MCDK involution, has led to the conclusion that the congenital anomalies previously identified in those with "congenital renal agenesis" extends to those with a history of MCKD 42,43,45 d. Screening for female anomalies of the internal genitalia is felt to be beneficial, as the management of female anomalies of the internal genitalia at the onset of puberty may prevent the symptoms of acute abdominal pain and dysmenorrhoea. 43 Opportunities for diagnosis in the asymptomatic female include an early pelvic US in the neonate with the assistance of vaginal infusion of saline.…”