Dystonia of the Oromandibular, Lingual and Laryngeal Areas

O’Dell, Karla; Sinha, Uttam K.

doi:10.5772/28356

Cited by 3 publications

(2 citation statements)

References 54 publications

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“…4 Initially dystonic episodes may be triggered by specific tasks such as eating, speaking or swallowing. [14][15] Jaw dystonia induced by speaking is very rare. 5 Later less specific motor tasks induce the symptoms and in advanced stages dystonic movements can occur at rest.…”

Section: Discussionmentioning

confidence: 99%

“…5 Later less specific motor tasks induce the symptoms and in advanced stages dystonic movements can occur at rest. [14][15] Sensory tricks in oromandibular dystonia include touching the face or inserting something such as candy or the tip of a pencil into the mouth. 4 The patient mentioned here had jawclosing variety of OMD triggered by speaking and partial improvement was demonstrable after putting a candy inside her mouth.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Jaw-Closing Oromandibular Dystonia Induced by Speaking in a Patient with Systemic Sclerosis

Hasan¹,

Abda

Yesmin³

et al. 2018

J Enam Med Col

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Oromandibular dystonia is a rare form of focal dystonia caused by involuntary spasms of masticatory, lingual and pharyngeal muscles. Here we describe a 53-year-old edentulous woman with systemic sclerosis who presented with dysarthria due to bilateral contraction of her masseter muscles during speaking. An anticholinergic medication was prescribed instead of botulinum toxin injection. Her condition markedly improved after medication. We suspected that edentulosity caused an impairment of proprioception in the oral cavity leading to subsequent development of dystonia.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Jaw-Closing Oromandibular Dystonia Induced by Speaking in a Patient with Systemic Sclerosis

Hasan¹,

Abda

Yesmin³

et al. 2018

J Enam Med Col

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show abstract

Botulinum neurotoxin a therapy efficacy and safety for oromandibular dystonia: a meta-analysis

et al. 2019

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Oromandibular dystonia: a serious side effect of capecitabine

et al. 2015

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BackgroundCapecitabine has activity against several types of cancer. In 10-15% of patients treated with capecitabine, treatment is discontinued because of serious adverse reactions, mostly within the first weeks of treatment.Case presentationA 56 year-old female patient presented at the emergency department after ten days of chemotherapy with progressive airway obstruction and complaints of numbness of the tongue. She also had difficulty swallowing and was unable to speak. Laboratory findings were completely normal and no co-medication was used, in particular no dopamine antagonists.A diagnosis of oromandibular dystonia due to capecitabine use was made. After the anticholinergic drug biperiden (Akineton) was given intravenously, complaints disappeared within twenty minutes. Due to an early discontinuation of biperiden, however, the symptoms of oromandibular dystonia recurred. Again, she was successfully treated with an anticholinergic drug. Capecitabine was permanently discontinued. Three days after the initial presentation the anticholinergic drug was stopped after which symptoms did not reappear.ConclusionThe case highlights the need for awareness that capecitabine may potentially lead to severe life-threatening complaints of oromandibular dystonia. We hypothesize that capecitabine passed the blood brain barrier which led to a disruption within the basal ganglia in this case. Prompt treatment with an anticholinergic drug and cessation of capecitabine in the patient case led to disappearance of complaints.

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Dystonia of the Oromandibular, Lingual and Laryngeal Areas

Cited by 3 publications

References 54 publications

Jaw-Closing Oromandibular Dystonia Induced by Speaking in a Patient with Systemic Sclerosis

Jaw-Closing Oromandibular Dystonia Induced by Speaking in a Patient with Systemic Sclerosis

Botulinum neurotoxin a therapy efficacy and safety for oromandibular dystonia: a meta-analysis

Oromandibular dystonia: a serious side effect of capecitabine

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