“…In spite of the fact that aniline is toxic, a plethora of its derivatives possess potent anticancer [1][2][3] anti-HIV, 4 antioxidant, [5][6][7] antifungal 8 and antimicrobial activities. 9 Aniline mustards have been reported to exhibit signicant antitumor properties and two representatives (chlorambucil and melphalan) of this class have achieved clinical status for cancer treatment. 1 Likewise, aniline containing sorafenib and its derivatives are promising antitumor agents.…”