E-cigarettes May Support Smokers With High Smoking-Related Risk Awareness to Stop Smoking in the Short Run: Preliminary Results by Randomized Controlled Trial

Abstract

E-cigarettes increased the stopping rate as well as the reduction of daily cigarettes in participants who continued smoking. In fact, although all participants reported a significant reduction of tobacco consumption compared to the baseline, the use of e-cigarettes allowed smokers to achieve a better result. It could be worthwhile to associate this device with new ICT-driven models of self-management support in order to enable people to better handle behavioral changes and side effects. This is true for ready-to-quit smokers (such as our participants) but can also be advantageous for less motivated smokers engaged in clinical settings.

Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation: a pragmatic, randomised trial

“…This change did not affect adherence (because product use at quit date was very high), but might limit the generalisable of the findings to policy environments where precessation use of NRT is not supported. Finally, serious adverse events were self-reported and similar to those reported in previous e-cigarette [3][4][5][6][7]9 and NRT trials. 16 However, the sample size was not sufficient to assess uncommon serious adverse events, nor was followup long enough to identify serious adverse events with a long lead-time.…”

“…1 E-cigarettes, mostly with nicotine, are used by smokers in many countries as an aid to quit smoking. 2 To date, seven clinical trials [3][4][5][6][7][8][9] (total N=8222; range n=68 to 6006) have investigated the efficacy and effectiveness of e-cigarettes for smoking cessation and overall suggest a net benefit. However, only four trials (N=7849; n=300 to 6006) had 6-month abstinence as a primary outcome 3,4,8,9 and only two trials (total N=6892) 8,9 tested a second-generation e-cigarette (capable of delivering nicotine more effectively than first-generation devices).…”

A Randomized Controlled Trial Evaluating the Efficacy of E-Cigarette Use for Smoking Cessation in the General Population: E3 Trial Design

“…9 Trials conducted internationally have suggested that e-cigarettes may be modestly more efficacious for smoking cessation than conventional nicotine replacement therapies (NRTs). [3][4][5][6] However, the generalizability of these findings to a North American general population remains unclear.…”

Increasing smoking cessation adherence: Do we need to consider the role of executive function and rumination?

“…increases depressive symptomatology (Criswell, Owen, Thornton, & Stanton, 2016), and consequently reduces motivation and impedes the quitting attempts (Lucchiari et al, 2016;Masiero, Renzi, Mazzocco, & Pravettoni, 2019;Masiero, Lucchiari, et al, 2019). Further, rumination has adverse effects on thinking and concentration, causing motivational deficits, which may inhibit the ability to take appropriate actions to resolve problems (Lyubomirsky et al, 1999).…”