2020
DOI: 10.1186/s12889-020-09572-x
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E-cigarettes use in the United States: reasons for use, perceptions, and effects on health

Abstract: Background Many researchers claim electronic cigarettes (e-cigarettes) to be a breakthrough invention for tobacco users that aspires to curb their addiction to conventional cigarettes. Claimed to be safer by their promoters, these smokeless devices have become increasingly popular since their arrival on the market among users of all ages, especially adolescents. This paper investigated the trends in e-cigarette usage since the time it arrived in the United States, highlighting the highest surge… Show more

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Cited by 143 publications
(102 citation statements)
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“…In addition, E-cigarette use can lead to hyposalivation resulting in tissue drying that promotes caries, periodontal disease, and other oral health problems [ 9 , 11 , 12 , 19 ]. The vegetable glycerin with other flavoring agents can increase microbial adhesion to enamel and promote biofilm formation, which results in a decreased enamel hardness [ 18 ]. Cinnamaldehyde can suppress the phagocytic function of neutrophils and macrophages; and inhibit the natural killer cells’ cell–killing ability of tumor cells, and ciliary beating of airway epithelial cells [ 20 , 21 ].…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…In addition, E-cigarette use can lead to hyposalivation resulting in tissue drying that promotes caries, periodontal disease, and other oral health problems [ 9 , 11 , 12 , 19 ]. The vegetable glycerin with other flavoring agents can increase microbial adhesion to enamel and promote biofilm formation, which results in a decreased enamel hardness [ 18 ]. Cinnamaldehyde can suppress the phagocytic function of neutrophils and macrophages; and inhibit the natural killer cells’ cell–killing ability of tumor cells, and ciliary beating of airway epithelial cells [ 20 , 21 ].…”
Section: Introductionmentioning
confidence: 99%
“…Nicotine, a wellknown vasoconstrictor, decreases gingival blood flow, and depresses cytokine production (IL-1β, IL-2, TNF-α, and IFN-γ), neutrophil number, and immune cell function, leading ultimately to periodontal disease and tooth loss [15][16][17]. The propylene glycol content of the E-cigarette breaks down into acetic and lactic acids, and other harmful compounds to the enamel and oral soft tissue [18]. In addition, E-cigarette use can lead to hyposalivation resulting in tissue drying that promotes caries, periodontal disease, and other oral health problems [9,11,12,19].…”
Section: Introductionmentioning
confidence: 99%
“…Of concern is an increasing body of evidence suggesting ENDS/ENNDS use may accrue a range of health risks for different age groups. [ 8 , 9 ] Constituents of e-liquids, such as propylene glycol and glycerine form toxic aldehydes when heated, of which the long-term effects of exposure remains unknown. [ 10 ] ENDS/ENNDS use can also impact on the respiratory system and is associated with adverse effects on the developing brain.…”
Section: Introductionmentioning
confidence: 99%
“…The performance of e-cigarettes varies among different brands [ 8 ], and the manufacture and components of E-cigarette product are regulated by FDA. It has been proposed that e-cigarettes serve as a strategy of smoking cessation or a less harmful replacement for conventional cigarette [ 9 , 10 ]. However, the data is inconclusive [ 11 ].…”
Section: Introductionmentioning
confidence: 99%