E-drug delivery: a futuristic approach

Yadav, Khushwant S.; Kapse-Mistry, Sonali; Peters, Godefridus J.; Mayur, Y.C.

doi:10.1016/j.drudis.2019.02.005

Cited by 23 publications

(10 citation statements)

References 33 publications

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“…In that sense, the use of electronics brings a new approach for integration of data from multiple sources. IntelliCap ® is the world's first intelligent electronic drug delivery and monitoring device, which combines controlled drug release, patient monitoring, and real-time wireless communication [111,112]. Since this electronic capsule features real-time wireless data recording, it can provide care givers the ability to monitor the progress of the capsule through the GI tract.…”

Section: Electronic Device-assisted Formulation Designmentioning

confidence: 99%

“…Since this electronic capsule features real-time wireless data recording, it can provide care givers the ability to monitor the progress of the capsule through the GI tract. Furthermore, simultaneous measurement of pH and transit, along with accurately targeting drug delivery, makes in vivo data available for a formulation design [111,112]. Consequently, IntelliCap ® technology provides a fast and convenient tool for the controlled drug release to specific sites in the GI tract.…”

Section: Electronic Device-assisted Formulation Designmentioning

confidence: 99%

“…In addition to many benefits, there are also some disadvantages associated with electronic capsules including high cost, manufacturing difficulties, biocompatibility issues, and potential risk of device failure [111,112]. Hence, there should be continuous efforts to overcome these disadvantages in order to make electronic delivery systems more widely compatible.…”

Section: Electronic Device-assisted Formulation Designmentioning

confidence: 99%

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Strategic Approaches for Colon Targeted Drug Delivery: An Overview of Recent Advancements

et al. 2020

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Colon targeted drug delivery systems have gained a great deal of attention as potential carriers for the local treatment of colonic diseases with reduced systemic side effects and also for the enhanced oral delivery of various therapeutics vulnerable to acidic and enzymatic degradation in the upper gastrointestinal tract. In recent years, the global pharmaceutical market for biologics has grown, and increasing demand for a more patient-friendly drug administration system highlights the importance of colonic drug delivery as a noninvasive delivery approach for macromolecules. Colon-targeted drug delivery systems for macromolecules can provide therapeutic benefits including better patient compliance (because they are pain-free and can be self-administered) and lower costs. Therefore, to achieve more efficient colonic drug delivery for local or systemic drug effects, various strategies have been explored including pH-dependent systems, enzyme-triggered systems, receptor-mediated systems, and magnetically-driven systems. In this review, recent advancements in various approaches for designing colon targeted drug delivery systems and their pharmaceutical applications are covered with a particular emphasis on formulation technologies.

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Section: Electronic Device-assisted Formulation Designmentioning

confidence: 99%

Section: Electronic Device-assisted Formulation Designmentioning

confidence: 99%

Section: Electronic Device-assisted Formulation Designmentioning

confidence: 99%

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Strategic Approaches for Colon Targeted Drug Delivery: An Overview of Recent Advancements

et al. 2020

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“…Although results are less accurate, solutions are far less invasive and obstructive [ 66 , 67 ]. Complementary to these sensors, diabetes management can reach a higher dimension, by actively monitoring blood glucose in diabetic patients and deliver, when necessary, insulin through in-body insulin pump actuators [ 68 ].…”

Section: Sensors: Definition and Taxonomymentioning

confidence: 99%

Sensors for Context-Aware Smart Healthcare: A Security Perspective

Batista

Moncusi

López-Aguilar³

et al. 2021

Sensors

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The advances in the miniaturisation of electronic devices and the deployment of cheaper and faster data networks have propelled environments augmented with contextual and real-time information, such as smart homes and smart cities. These context-aware environments have opened the door to numerous opportunities for providing added-value, accurate and personalised services to citizens. In particular, smart healthcare, regarded as the natural evolution of electronic health and mobile health, contributes to enhance medical services and people’s welfare, while shortening waiting times and decreasing healthcare expenditure. However, the large number, variety and complexity of devices and systems involved in smart health systems involve a number of challenging considerations to be considered, particularly from security and privacy perspectives. To this aim, this article provides a thorough technical review on the deployment of secure smart health services, ranging from the very collection of sensors data (either related to the medical conditions of individuals or to their immediate context), the transmission of these data through wireless communication networks, to the final storage and analysis of such information in the appropriate health information systems. As a result, we provide practitioners with a comprehensive overview of the existing vulnerabilities and solutions in the technical side of smart healthcare.

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“…6,7 . Additionally, these HWDs can be used for the delivery of drugs in a more controlled and efficient manner in comparison to traditional drug delivery systems [14][15][16] .…”

Section: Introductionmentioning

confidence: 99%

Advances in healthcare wearable devices

et al. 2021

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Wearable devices have found numerous applications in healthcare ranging from physiological diseases, such as cardiovascular diseases, hypertension and muscle disorders to neurocognitive disorders, such as Parkinson’s disease, Alzheimer’s disease and other psychological diseases. Different types of wearables are used for this purpose, for example, skin-based wearables including tattoo-based wearables, textile-based wearables, and biofluidic-based wearables. Recently, wearables have also shown encouraging improvements as a drug delivery system; therefore, enhancing its utility towards personalized healthcare. These wearables contain inherent challenges, which need to be addressed before their commercialization as a fully personalized healthcare system. This paper reviews different types of wearable devices currently being used in the healthcare field. It also highlights their efficacy in monitoring different diseases and applications of healthcare wearable devices (HWDs) for diagnostic and treatment purposes. Additionally, current challenges and limitations of these wearables in the field of healthcare along with their future perspectives are also reviewed.

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E-drug delivery: a futuristic approach

Cited by 23 publications

References 33 publications

Strategic Approaches for Colon Targeted Drug Delivery: An Overview of Recent Advancements

Strategic Approaches for Colon Targeted Drug Delivery: An Overview of Recent Advancements

Sensors for Context-Aware Smart Healthcare: A Security Perspective

Advances in healthcare wearable devices

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