E-pipe use leading to lipoid pneumonia in Europe

Kessler, Anne-Catherine; Dommann, Corina; Nussbaumer-Ochsner, Yvonne

doi:10.1136/thoraxjnl-2019-214391

Cited by 5 publications

(5 citation statements)

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“…Existen otras exposiciones, la mayoría de índole laboral, como puede ser la manipulación de lubricantes industriales, pesticidas o pinturas 1 , 2 . El consumo de cigarrillos electrónicos también se ha relacionado con la patogenia de la enfermedad 3 .…”

Section: Discussionunclassified

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Exogenous lipoid pneumonia and anorexia nervosa: a case report

Sanz

Alvarez

Lamana

et al. 2022

An Sist Sanit Navar

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Resumen La neumonía lipoidea exógena es una entidad infrecuente y con una presentación clínica inespecífica. Su diagnóstico temprano es clave para prevenir la fibrosis pulmonar que produce su cronificación. Presentamos el proceso diagnóstico de una paciente de 51 años, con clínica de tos con expectoración amarillenta, sin síntomas de infección ni fiebre, de larga evolución. En la tomografía axial computarizada se observaron infiltrados pulmonares bilaterales de tipo alveolar. Se realizó un lavado broncoalveolar en el que se obtuvo un material amarillento de origen desconocido, que no permitió alcanzar ninguna conclusión clara. La criobiopsia pulmonar fue la prueba clave que llevó al diagnóstico de neumonía lipoidea exógena, en probable relación con la anorexia con hábito purgativo que la paciente sufría de forma crónica. Hallado el origen del problema, la paciente se encuentra actualmente en proceso de recuperación y cambio de hábitos, sin tos ni expectoración.

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Section: Discussionunclassified

“…Los análisis de sangre son habitualmente normales, aunque pueden mostrar leucocitosis y un aumento de la velocidad de sedimentación globular. Las pruebas de función pulmonar pueden mostrar un patrón restrictivo, o ser normales 3 .…”

Section: Discussionunclassified

Exogenous lipoid pneumonia and anorexia nervosa: a case report

Sanz

Alvarez

Lamana

et al. 2022

An Sist Sanit Navar

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“…Since then, most cases have been reported in patients with a predisposition to aspiration, such as mental retardation, cleft palate, anatomic or functional abnormality in swallowing. 4 , 5 , 6 , 7 , 8 But there have been some reports of exogenous LP caused by traditional folk remedies. 9 Various causative agents can cause LP, depending on local life style and cultural differences among patients.…”

Section: Introductionmentioning

confidence: 99%

“…Historically, Yeung et al 4 reported the first cases of exogenous lipoid pneumonia in one adult and in four children after chronic exposure to mineral oil nose drops and laxatives. Since then, most cases have been reported in patients with a predisposition to aspiration, such as mental retardation, cleft palate, anatomic or functional abnormality in swallowing 4–8 . But there have been some reports of exogenous LP caused by traditional folk remedies 9 .…”

Section: Introductionmentioning

confidence: 99%

The effect of therapeutic bronchoalveolar lavage in combination with glucocorticoids on children with acute exogenous lipoid pneumonia

Yang

et al. 2023

Clinical Respiratory J

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Background Exogenous lipoid pneumonia (ELP) is a rare disease caused by the inhalation of oily materials in the alveoli with the pathological characterization by the presence of laden‐lipid macrophages in the respiratory specimens. At present, the treatment norm for ELP has not well defined, and so the aim of this study is to evaluate the effect of bronchoalveolar lavage in combination with glucocorticoids on children with ELP. Methods and Materials We retrospectively reviewed 17 children with a confirmed history of exogenous oily materials aspiration, admitted to the First Affiliated Hospital of Guangzhou Medical University from June 2012 to December 2021. Clinical features, blood investigations, tomographic evaluations, therapeutic bronchoalveolar lavage and glucocorticoids use were carried out at the beginning of therapy and throughout a follow‐up period. Results The included children are the median age of 2 years. Fever, dypnea and tachypnea were the most common symptoms. The most common radiological features were airspace consolidations (15, 93.75%). Chest CT scans showed areas of consolidation with air bronchogram (15, 93.75%), poorly defined centrilobular nodules (13, 81.25%), areas of ground‐glass attenuation (11, 68.75%) and ‘crazy‐paving’ pattern (6, 37.5%) in the both lower, right middle lung lobes. Neutrophil percentage of peripheral blood and bronchoalveolar lavage fluid exhibited a significantly higher than the normal range. After treatment with multiple bronchoalveolar lavages and local administration of budesonide during the hospital stay, taken by oral prednisolone (1 ~ 2 mg/kg) after discharge, all of children became asymptomatic and presented normal radiological imagings in the follow‐up period. Conclusion The most frequently findings in the CT scan of ELP were consolidations and ground‐glass attenuation in the both lower and right middle lung lobes. Multiple bronchoalveolar lavages in combination with oral prednisolone for children who had a confirmed history of exogenous oily substances ingestion were an efficient and safe for the clearance of oily materials from the lung and the prevention of fibrosis. This strategy contributed to reducing the damage of ELP in children patients.

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“…4 Since then, most cases have been reported in patients with a predisposition to aspiration, such as mental retardation, cleft palate, anatomic or functional abnormality in swallowing. [4][5][6][7][8] But, there have been some reports of exogenous LP caused by traditional folk remedies. 9 Various causative agents can cause LP, depending on local life style and cultural differences among patients.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Therapeutic Bronchoalveolar Lavage in Combination with Glucocorticoids on Children with Acute Exogenous Lipoid Pneumonia

Yang

et al. 2022

Preprint

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Background: Exogenous lipoid pneumonia(ELP) is a rare disease caused by the inhalation of oily materials in the alveoli with the pathological characterization by the presence of laden-lipid macrophages in the respiratory specimens. At present, the treatment norm for ELP has not well defined, and so the aim of this study is to evaluate the effect of bronchoalveolar lavage in combination with glucocorticoids on children with ELP. Methods and Materials: We retrospectively reviewed 17 children with a confirmed history of exogenous oily materials aspiration, admitted to the First Affiliated Hospital of Guangzhou Medical University from June 2012 to December 2021. Clinical features, blood investigations, tomographic evaluations, therapeutic bronchoalveolar lavage and glucocorticoids use were carried out at the beginning of therapy and throughout a follow-up period. Results: The included children are the median age of 2 years. Fever, dypnea and tachypnea were the most common symptoms. The most common radiological features were airspace consolidations(15, 93.75%). Chest CT scans showed areas of consolidation with air bronchogram(15, 93.75%), Poorly defined centrilobular nodules(13, 81.25%), areas of ground-glass attenuation(11, 68.75%), and ‘crazy-paving’ pattern(6, 37.5%) in the both lower, right middle lung lobes. Neutrophil percentage of peripheral blood and bronchoalveolar lavage fluid exhibited a significantly higher than the normal range. After treatment with multiple bronchoalveolar lavages and local administration of budesonide during the hospital stay, taken by oral prednisolone(1~2mg/kg) after discharge,all of children became asymptomatic and presented normal radiological imagings in the follow-up period. Conclusion:The most frequently findings in the CT scan of ELP were consolidations and ground-glass attenuation in the both lower and right middle lung lobes.Multiple bronchoalveolar lavages in combination with oral prednisolone for children who had a confirmed history of exogenous oily substances ingestion was an efficient and safe for the clearance of oily materials from the lung and the prevention of fibrosis. This strategy contributed to reducing the damage of ELP in children patients.

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E-pipe use leading to lipoid pneumonia in Europe

Cited by 5 publications

References 2 publications

Exogenous lipoid pneumonia and anorexia nervosa: a case report

Exogenous lipoid pneumonia and anorexia nervosa: a case report

The effect of therapeutic bronchoalveolar lavage in combination with glucocorticoids on children with acute exogenous lipoid pneumonia

The Effect of Therapeutic Bronchoalveolar Lavage in Combination with Glucocorticoids on Children with Acute Exogenous Lipoid Pneumonia

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