Thrombotic complications of SARS-CoV-2 have been increasingly recognized
as an important component of COVID-19 in adults; however, they have been
less evident in children. We report a case of a teenager with positive
SARS‐CoV‐2 RT–PCR and underlying prothrombotic risk factors, including
aromatase inhibitor therapy, who developed deep vein thrombosis
resulting in pulmonary embolism. Laboratory tests revealed deranged
coagulation parameters (high D-dimers and Factor VIII and low
antithrombin). The patient required intensive care and was managed with
anticoagulants, dexamethasone and antithrombin concentrate. Clinical
condition and hemostatic profile gradually improved. A review of the
available literature for similar cases is presented.